A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities

  • Jose de Leon

Table of contents

  1. Front Matter
    Pages i-xxxi
  2. Jose de Leon
    Pages 1-17

About this book

Introduction

Emotional, behavioral, and neuropsychiatric conditions are common in individuals with intellectual disabilities (IDs), most notably epilepsy, aggression, self-injurious behaviors, and bipolar and other mood disorders. Despite the prevalence of such problems, there is a scarcity in the literature of reliable information on medical treatments for those with IDs.

A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities provides a detailed framework for prescribing for this challenging population. Featuring the most up-to-date information on factors that inform prescribing, the Guide addresses basic issues and controversies (e.g., the rift between evidence-based and personalized medicine) in treating adults with cognitive deficits. Clients' specific needs are emphasized in developing appropriate and effective pharmacological intervention for improved outcomes and quality of life. Drugs discussed in the Guide include carbamazepine, clonazepam, diazepam, ethosuximide, felbamate, gabapentin, lacosamide, lamotrigine, levetiracetam, lithium, lorazepam, oxcarbazepine, phenobarbital, phenytoin, pregabalin, primidone, rufinamide,  tiagabine, topiramate, valproate, and zonisamide. For each of these compounds, the guidelines cover:

  • Indications for use; relative and absolute contraindications.
  • Assessment during treatment; therapeutic drug monitoring; warning signs and symptoms for caretakers.
  • Dosage: administration; initial and maximum recommended dosage; modifications associated with drug-drug interactions, personal characteristics, and (where appropriate) genetic variations.
  • Adverse drug reactions: common, relatively uncommon, and potentially lethal, plus risk of metabolic syndrome.
  • Guidelines for discontinuation.
  • References, tables, and drug utilization reviews.

A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities is an indispensable decision-making reference for psychiatrists, neuropsychologists, psychopharmacologists, neurologists, internists, and clinical psychologists.

Keywords

Aggression and intellectual disabilities Anticonvulsants and intellectual disabilities Antiepileptic drugs and intellectual disabilities Bipolar disorder and intellectual disabilities Carbamazepine and intellectual disabilities Clonazepam and intellectual disabilities Diazepam and intellectual disabilities Epilepsy ethosuximide and intellectual disabilities Felbamate and intellectual disabilities Gabapentin and intellectual disabilities Intellectual disabilities Lacosamide and intellectual disabilities Lamotrigine and intellectual disabilities Levetiracetam and intellectual disabilities Lithium and intellectual disabilities Lorazepam and intellectual disabilities Mental retardation and intellectual disabilities Mood disorders and intellectual disabilities Mood stabilizers and intellectual disabilities Oxcarbazepine and intellectual disabilities Phenobarbital and intellectual disabilities Phenytoin and intellectual disabilities Pregabalin and intellectual disabilities Primidone and intellectual disabilities Rufinamide and intellectual disabilities Seizures and intellectual disabilities Self-injurious behavior and intellectual disabilities Tiagabine and intellectual disabilities Topiramate and intellectual disabilities Valproic acid and intellectual disabilities Zonisamide and intellectual disabilities

Editors and affiliations

  • Jose de Leon
    • 1
  1. 1.College of Medicine, Department of PsychiatryUniversity of KentuckyLexingtonUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4614-2012-5
  • Copyright Information Springer Science+Business Media, LLC 2012
  • Publisher Name Springer, Boston, MA
  • eBook Packages Medicine
  • Print ISBN 978-1-4614-2011-8
  • Online ISBN 978-1-4614-2012-5
  • About this book