Engineering Biomaterials for Regenerative Medicine

Novel Technologies for Clinical Applications

  • Sujata K. Bhatia

Table of contents

  1. Front Matter
    Pages i-x
  2. Cellular Recruitment and Delivery

    1. Front Matter
      Pages 1-1
    2. Brooke N. Mason, Joseph P. Califano, Cynthia A. Reinhart-King
      Pages 19-37
  3. Oxygen Delivery

    1. Front Matter
      Pages 39-39
    2. Whitney L. Stoppel, Susan C. Roberts
      Pages 41-86
  4. Tuning of Mechanical Properties

    1. Front Matter
      Pages 87-87
    2. Santanu Kundu, Edwin P. Chan
      Pages 89-125
    3. Gregory N. Tew, Surita R. Bhatia
      Pages 127-140
  5. Control of Inflammation and Host Response

    1. Front Matter
      Pages 141-141
    2. Anjelica L. Gonzalez-Simon, Omolola Eniola-Adefeso
      Pages 143-159
    3. Paritosh P. Wattamwar, Thomas D. Dziubla
      Pages 161-192
  6. Biologically Inspired Materials for Tissue Regeneration

    1. Front Matter
      Pages 193-193
    2. Woo Kyung Cho, Maria José Maio Nunes Pereira, Nora Lang, Kyungheon Lee, Shwetha Mureli, Andreas Zumbuehl et al.
      Pages 195-223
    3. Christopher McGann, Kristi Kiick
      Pages 225-250
  7. Clinical Applications of Tissue Regeneration

    1. Front Matter
      Pages 251-251
    2. Alexandra J. E. Farran, Zhixiang Tong, Robert L. Witt, Xinqiao Jia
      Pages 253-284
    3. Kory Blocker, Millicent Sullivan
      Pages 285-319

About this book

Introduction

Regeneration of tissues and organs remains one of the great  challenges of clinical medicine, and physicians are constantly seeking better methods for tissue repair and replacement.   Tissue engineering and regenerative medicine have been investigated for virtually every organ system in the human body, and progress  is made possible by advances in materials science, polymer chemistry, and molecular biology.  This book reviews the current status of biomaterials for regenerative medicine, and highlights advances in both basic science and clinical practice.  The latest methods for regulating the biological and chemical composition of biomaterials are described, together with  techniques for modulating mechanical properties of engineered constructs.  Contributors delineate methods for guiding the host response to implantable materials, and explain the use of biologically-inspired materials for optimal biological functionality and compatibility.  The book culminates in a discussion of the clinical applications of regenerative medicine.

By integrating engineering and clinical medicine, Engineering Biomaterials for Regenerative Medicine  examines how tissue engineering and regenerative medicine can be translated into successful therapies to bridge the gap between laboratory and clinic.  The book will aid materials scientists and engineers in identifying research priorities to fulfill clinical needs, and  will also enable physicians to understand novel biomaterials that are emerging in the clinic.  This integrated approach also gives engineering students a sense of the excitement and relevance of materials science  in the development of novel therapeutic strategies.

Details strategies for addressing specific disease states with tissue engineering and regenerative medicine

Discusses the latest generation of regenerative biomaterial

Keywords

PLA-PEO-PLA hydrogels PLA-PEO-PLA hydrogels adhesion behavior biomaterials adhesion behavior biomaterials biomaterials surface modification biomaterials surface modification chitosan-based delivery system engineered biomaterials disease engineering clinical medicine gecko tape heparin-functionalized materials host response biomaterials materials science healthcare matrix stiffness tissue engineering matrix stiffness tissue engineering non-viral gene delivery oxygen supply tissue engineering oxygen supply tissue engineering regenerative medicine disease regenerative medicine trauma tissue engineering regenerative vocal fold tissue engineering wound healing response biomaterials

Editors and affiliations

  • Sujata K. Bhatia
    • 1
  1. 1., School of Engineering and Applied SciencHarvard UniversityCambridgeUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4614-1080-5
  • Copyright Information Springer Science+Business Media, LLC 2012
  • Publisher Name Springer, New York, NY
  • eBook Packages Chemistry and Materials Science
  • Print ISBN 978-1-4614-1079-9
  • Online ISBN 978-1-4614-1080-5
  • About this book