Control of Cell Fate in the Circulatory and Ventilatory Systems

  • Marc Thiriet

Table of contents

  1. Front Matter
    Pages i-x
  2. Marc Thiriet
    Pages 5-83
  3. Marc Thiriet
    Pages 85-176
  4. Marc Thiriet
    Pages 177-277
  5. Marc Thiriet
    Pages 279-327
  6. Marc Thiriet
    Pages 329-356
  7. Marc Thiriet
    Pages 357-417
  8. Back Matter
    Pages 419-536

About this book


The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to nano- and microscopic events in a corrector scheme of regulated mechanisms. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning.

Volumes 1 and 2 are devoted to cell organization and fate, as well as activities that are autoregulated and/or controlled by the cell environment. Volume 1 examined cellular features that allow adaptation to environmental conditions. Volume 2 begins with a survey of the cell types of the nervous and endocrine systems involved in the regulation of the vasculature and respiratory tract and growth factors.  It then describes major cell events in the circulatory and ventilatory systems, such as cell growth, proliferation, migration, and death. Circadian cycles that drive rhythmic gene transcription are also covered.

  • Describes cell types, functions, and fate in the regulated activities of the circulatory and respiratory systems
  • Presents applications of mechanics and mathematics for an understanding and prediction of function in health and disease
  • Integrates biology, chemistry, and physics for a multidisciplinary understanding of physiological flows


blood flow prediction cardiovascular systems modeling cell cytoskeleton cell environment cell membrane cell signalling cell types systems cell types tract macroscopic blood flow behavior modeling respiratory function modeling simulation of flows physiological flows ventilatory systems modeling

Authors and affiliations

  • Marc Thiriet
    • 1
  1. 1.Laboratoire Jacques-Louis Lions, Institut Universitaire de FranceUniversité Pierre et Marie CurieParisFrance

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Buisness Media, LLC 2012
  • Publisher Name Springer, New York, NY
  • eBook Packages Physics and Astronomy
  • Print ISBN 978-1-4614-0328-9
  • Online ISBN 978-1-4614-0329-6
  • Buy this book on publisher's site