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DNA Methylation

Biochemistry and Biological Significance

  • Aharon Razin
  • Howard Cedar
  • Arthur D. Riggs

Part of the Springer Series in Molecular Biology book series (SSMOL)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Aharon Razin, Howard Cedar, Arthur D. Riggs
    Pages 1-10
  3. Robert Yuan, Daniel L. Hamilton
    Pages 11-37
  4. Hamilton O. Smith, Samuel V. Kelly
    Pages 39-71
  5. Robert Yuan, Hamilton O. Smith
    Pages 73-80
  6. M. G. Marinus
    Pages 81-109
  7. Robert H. Grafstrom, Daniel L. Hamilton, Robert Yuan
    Pages 111-126
  8. Howard Cedar
    Pages 147-164
  9. Peter A. Jones
    Pages 165-187
  10. Detlev Jähner, Rudolf Jaenisch
    Pages 189-219
  11. Walter Doerfler, Klaus-Dieter Langner, Inge Kruczek, Lily Vardimon, Doris Renz
    Pages 221-247
  12. Kathleen F. Conklin, Mark Groudine
    Pages 293-351
  13. Joel Yisraeli, Moshe Szyf
    Pages 353-378
  14. Back Matter
    Pages 379-392

About this book

Introduction

During the past few decades we have witnessed an era of remarkable growth in the field of molecular biology. In 1950 very little was known of the chemical constitution of biological systems, the manner in which information was trans­ mitted from one organism to another, or the extent to which the chemical basis of life is unified. The picture today is dramatically different. We have an almost bewildering variety of information detailing many different aspects of life at the molecular level. These great advances have brought with them some breath-taking insights into the molecular mechanisms used by nature for rep­ licating, distributing and modifying biological information. We have learned a great deal about the chemical and physical nature of the macromolecular nucleic acids and proteins, and the manner in which carbohydrates, lipids and smaller molecules work together to provide the molecular setting of living sys­ tems. It might be said that these few decades have replaced a near vacuum of information with a very large surplus. It is in the context of this flood of information that this series of monographs on molecular biology has been organized. The idea is to bring together in one place, between the covers of one book, a concise assessment of the state of the subject in a well-defined field. This will enable the reader to get a sense of historical perspective-what is known about the field today-and a description of the frontiers of research where our knowledge is increasing steadily.

Keywords

Activation DNA biochemistry biology enzymes gene expression methylation molecular biology molecular mechanisms nucleic acid protein proteins regulation replication transcription

Editors and affiliations

  • Aharon Razin
    • 1
  • Howard Cedar
    • 2
  • Arthur D. Riggs
    • 3
  1. 1.Department of Cellular BiologyThe Hebrew University Hadassah Medical SchoolJerusalemIsrael
  2. 2.Department of Cellular BiochemistryThe Hebrew University Hadassah Medical SchoolJerusalemIsrael
  3. 3.Beckman Research Institute of the City of HopeDuarteUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4613-8519-6
  • Copyright Information Springer-Verlag New York 1984
  • Publisher Name Springer, New York, NY
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-8521-9
  • Online ISBN 978-1-4613-8519-6
  • Series Print ISSN 0942-6523
  • Buy this book on publisher's site