Polycystic Ovary Syndrome

  • R. Jeffrey Chang

Part of the Serono Symposia USA book series (SERONOSYMP)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Jimmy L. Spearow
    Pages 1-20
  3. Jonathan L. Tilly, Anne N. Hirshfield
    Pages 37-50
  4. Frederick Naftolin, Angela Palumbo, John R. Pepperell
    Pages 71-88
  5. Carol-Beth Book, Andrea Dunaif
    Pages 117-125
  6. David A. Ehrmann, Jeppe Sturis, Maria M. Byrne, Robert L. Rosenfield, Kenneth S. Polonsky
    Pages 126-141
  7. Stephen G. Hillier, Masa Tetsuka, Fernando Miró
    Pages 142-153
  8. Stephen Franks, Debbie S. Willis, Helen D. Mason, Carole M.-T. Gilling-Smith
    Pages 154-164
  9. Bruce R. Carr, Elizabeth A. McGee, Chiravudh Sawetawan, William E. Rainey
    Pages 165-195
  10. William E. Rainey, Tina C. Lavranos, Ann M. Corbould, Ray J. Rodgers, Bruce R. Carr
    Pages 196-207
  11. Denis A. Magoffin, Sanjay K. Agarwal, Artur J. Jakimiuk
    Pages 208-222
  12. Linda C. Giudice, H. J. H. M. van Dessel, Nicholas A. Cataldo, Yasmin A. Chandrasekher, O. W. Stephanie Yap, Bart C. J. M. Fauser
    Pages 223-244
  13. Anthony P. Cheung, John K. H. Lu, R. Jeffrey Chang
    Pages 254-264
  14. Marco Filicori, Graciela E. Cognigni
    Pages 265-271
  15. Jeffrey L. Deaton, Kathleen A. Miller, Robin A. Dempsey, Traci Spencer
    Pages 272-283

About this book

Introduction

The term polycystic ovary syndrome (peOS) is meant to describe a clinical endocrinopathy characterized by menstrual irregularity and evidence of hyperandrogenism. While recognized since the 1800s, a clinical composite was not constructed until 1935 when Stein and Leventhal reported their findings of seven women with infertility, menstrual dysfunction, hirsutism, and enlarged ovaries. Notably, the ovaries contained numerous multiple cysts and the ovarian capsule was thickened. At the time, this preciseness of definition was sufficient to entitle the entity Stein-Leventhal syndrome. Subsequently, over the intervening years as investigators attempted to un­ ravel the pathophysiology and genesis of this disorder and the number of reported studies increased, there ensued a gradual and distinct terminologic conversion to polycystic ovary syndrome, which, whether intentional or not, connoted a less well-defined condition. Perhaps this is appropriately so, given the seemingly broadening spectrum of clinical presentations and the continuing debate over what constitutes peos. The expansive new knowledge about peos was discussed to a significant degree at an international symposium organized by Serono Symposia USA and held in Boston in the late spring of 1995. Ovarian physiology, including the fate of the follicular unit, was a central focus with several presentations on the genesis, growth, and death of ovarian cellular components. A discus­ sion of the regulation of ovarian cell function was also highlighted and comprised a major portion of the program.

Keywords

embryo growth growth factor hormone hormones in vitro fertilization insulin insulin resistance insulin-like metabolism regulation steroid

Editors and affiliations

  • R. Jeffrey Chang
    • 1
  1. 1.Department of Obstetrics and Gynecology, School of MedicineUniversity of California, DavisSacramentoUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4613-8483-0
  • Copyright Information Springer-Verlag New York 1996
  • Publisher Name Springer, New York, NY
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-8485-4
  • Online ISBN 978-1-4613-8483-0
  • About this book