Regulatory Function of Adenosine

Proceedings of the International Symposium on Adenosine, Charlottesville, Virginia, June 7–11,1982

  • Robert M. Berne
  • Theodore W. Rall
  • Rafael Rubio

Part of the Developments in Pharmacology book series (DIPH, volume 2)

Table of contents

  1. Front Matter
    Pages i-xxi
  2. Adenosine Receptors

  3. Adenosine Metabolism and Transport

    1. Front Matter
      Pages 115-115
    2. John M. Lowenstein, Ming-Kun Yu, Yoshitsugo Naito
      Pages 117-131
    3. Peter G. W. Plagemann, Robert M. Wohlhueter
      Pages 179-201
    4. Alan R. P. Paterson, Ewa S. Jakobs, Eric R. Harley, Nai-Wu Fu, Morris J. Robins, Carol E. Cass
      Pages 203-220
  4. Adenosine and Regulation of Immune Function

    1. Front Matter
      Pages 221-221
    2. Stephen H. Polmar, Ruth E. Birch, Raya Mandler, Stephen A. Rudolph
      Pages 249-259
    3. Thomas P. Zimmerman, Gerald Wolberg, Gail S. Duncan
      Pages 261-273
  5. Adenosine and Platelet Function

    1. Front Matter
      Pages 275-275
    2. D. C. B. Mills, D. E. Macfarlane, B. W. G. Lemmex, R. J. Haslam
      Pages 277-289
  6. Vascular Effects of Adenosine

    1. Front Matter
      Pages 291-291
    2. Robert M. Berne, H. Richard Winn, Robert M. Knabb, Stephen W. Ely, Rafael Rubio
      Pages 293-317
    3. Rafael Rubio, Maureen T. Knabb, Tokumasa Tsukada, Robert M. Berne
      Pages 319-332
    4. Jeremy D. Pearson, Paul G. Hellewell, John L. Gordon
      Pages 333-345
  7. Influence of Adenosine on Cardiac and Renal Function

    1. Front Matter
      Pages 361-361
    2. James G. Dobson Jr., Richard A. Fenton
      Pages 363-376
    3. Luiz Belardinelli, Alexander West, Richard Crampton, Robert M. Berne
      Pages 377-398
    4. H. Osswald
      Pages 399-415
  8. Actions of Adenosine in the Nervous System

    1. Front Matter
      Pages 417-417
    2. John W. Phillis, Peter H. Wu
      Pages 419-437
    3. Peter Schubert, Kevin Lee, Martin Reddington, Georg Kreutzberg
      Pages 439-454
    4. Trevor W. Stone
      Pages 467-477
    5. Bertil B. Fredholm, Lars E. Gustafsson, Per Hedqvist, Alf Sollevi
      Pages 479-495
  9. Back Matter
    Pages 497-558

About this book


The principal objective of this symposium was to bring together investigators from all over the world who work in diverse areas of research but share a common interest in the physiologic and pathophysiologic funetions of the nueleoside adenosine. In 1978, the "International Conference on Physiological and Regulatory Funetions of Adenosine and Adenine Nueleotides," held in Banff, Canada, served as an effective catalyst in enabling scientists with differ­ ent points of view to exchange information and ideas on this subject. Since 1978, the amount of research on different as peets of adenosine metabolism, mechanism of action, transport, and function in various tissues (in both nor­ maI and abnormal states) has increased exponentially, and there was an urgent need for another meeting for updating information on this burgeoning subject. The focus of the meeting was extremely sharp, but the scope of the subject material was very broad. Scientists categorized as chemists, biochemists, physiologists, pharmacologists, and immunologists, working with cells and eelI fragments, with tissues such as heart, brain, musele, fat, kidney, and with human beings having immune deficiency diseases participated in the sym­ posium. They had an opportunity to air their differences, reinforce their areas of agreement, and, most important, they educated each other with respeet to research on adenosine; it is hoped that they also enriched their own research programs from the information they gained from their fellow participants.


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Editors and affiliations

  • Robert M. Berne
    • 1
  • Theodore W. Rall
    • 2
  • Rafael Rubio
    • 1
  1. 1.Department of PhysiologyUniversity of Virginia School of MedicineCharlottesvilleUSA
  2. 2.Department of PharmacologyUniversity of Virginia School of MedicineCharlottesvilleUSA

Bibliographic information