The Biology of Alcoholism

Vol. 7 The Pathogenesis of Alcoholism: Biological Factors

  • Benjamin Kissin
  • Henri Begleiter

Table of contents

  1. Front Matter
    Pages i-xxix
  2. Gerald E. McClearn
    Pages 1-30
  3. William M. Grove, Remi J. Cadoret
    Pages 31-56
  4. David H. Ross, Kennon M. Garrett
    Pages 57-75
  5. Roy A. Wise, Aryeh Routtenberg
    Pages 77-105
  6. Gail Winger, Alice M. Young, James H. Woods
    Pages 107-131
  7. Boris Tabakoff, Paula L. Hoffman
    Pages 199-252
  8. C. J. Peter Eriksson, Richard A. Deitrich
    Pages 253-283
  9. Bernice Porjesz, Henri Begleiter
    Pages 415-483
  10. Christopher Ryan, Nelson Butters
    Pages 485-538
  11. Ann Pytkowicz Streissguth, Joan C. Martin
    Pages 539-589
  12. Back Matter
    Pages 613-635

About this book


The previous volume, The Pathogenesis of Alcoholism: Psychosocial Factors, attempted to describe the interaction of biological, psychological, and social factors that lead to the initiation and perpetuation of alcoholism. The preface to that volume presented our particular view of the bio-. psycho-social interaction as a progressive process in which earlier developments produce new pathogenetic mechanisms, which in turn lead to still other cyclical feedback activities. Although influences from each of the three phenomenologic levels are at work during each stage of the clinical course, it would appear that social factors are most significant in the early phase, psychological factors at the intermediate level, and biological ones toward the end. These differences are only relative, however, for influences of all three types surely are operative during all stages of the syndrome. This appears to be particularly true for the biological parameters of activity. Don Goodwin (1976), who has supplied much of the data that support the role of hereditary factors in alcoholism, is wont to say that all living behavior is biological-by definition. The operational evidence for this is perhaps more evident in alcoholism than in other syndromes. For example, the general social indifference of many Asians to alcohol may reflect the presence of an atypical isoenzyme of alcohol dehydrogenase rather than some independently derived cultural norm.


Syndrom alcohol alcoholism brain diagnosis growth memory nervous system pharmacology prevention syndromes

Editors and affiliations

  • Benjamin Kissin
    • 1
  • Henri Begleiter
    • 1
  1. 1.Downstate Medical CenterBrooklynUSA

Bibliographic information