Principles of Metabolic Control in Mammalian Systems

  • Robert H. Herman
  • Robert M. Cohn
  • Pamela D. McNamara

Table of contents

  1. Front Matter
    Pages i-xxi
  2. Robert H. Herman
    Pages 1-61
  3. Robert M. Cohn, Michael J. Palmieri, Pamela D. McNamara
    Pages 63-92
  4. Robert M. Cohn
    Pages 93-133
  5. Robert M. Cohn, John R. Yandrasitz
    Pages 135-169
  6. Robert M. Cohn, Pamela D. McNamara, Robert H. Herman
    Pages 171-219
  7. F. John Ballard
    Pages 221-263
  8. Robert H. Herman
    Pages 265-294
  9. Robert M. Cohn, Marc Yudkoff, Pamela D. McNamara
    Pages 295-312
  10. Robert M. Cohn, Pamela D. McNamara
    Pages 313-335
  11. Pamela D. McNamara, Božena Ožegović
    Pages 373-437
  12. Harold I. Friedman
    Pages 439-493
  13. Ifeanyi J. Arinze, Richard W. Hanson
    Pages 495-534
  14. Robert H. Herman, O. David Taunton
    Pages 535-620
  15. Robert H. Herman, Robert M. Cohn
    Pages 621-657
  16. Back Matter
    Pages 659-669

About this book


In this work we present the basic principles of metabolic control which we hope will serve as a foundation for the vast array of factual matter which the biochemist and the physician engaged in metabolic research must accumulate. Accordingly, we attempt to set forth these principles, along with sufficient explanation, so that the reader may apply them to the ever-expanding literature of biochemistry. If we are successful, this will provide a theoretical approach which can be applied to any given set of metabolic reactions. It is impossible to enumerate each and every biochemical reaction and pathway since such a work would be too unwieldy for efficient use. Rather, we hope our presentation of the principles of metabolic control will be sufficiently basic to be of lasting usefulness no matter how detailed biochemistry may become. We would like to be able to con­ dense biochemistry into a theoretical biology that will not only allow for the general treatment of any given reaction but will enable predic­ tions to be made as to the existence of necessary pathways and the con­ sequences of altered control. Such is not possible today, but this may be accomplished in the future. We believe it is now possible to institute the beginnings of such a theoretical biology.


behavior biochemistry biology cell environment enzyme genes metabolism protein thermodynamics tissue water

Editors and affiliations

  • Robert H. Herman
    • 1
  • Robert M. Cohn
    • 2
  • Pamela D. McNamara
    • 2
  1. 1.Letterman Army Institute of ResearchSan FranciscoUSA
  2. 2.University of PennsylvaniaPhiladelphiaUSA

Bibliographic information