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Plasma Fractionation and Blood Transfusion

Proceedings of the Ninth Annual Symposium on Blood Transfusion, Groningen, 1984, organized by the Red Cross Blood Bank Groningen-Drenthe

  • C. Th. Smit Sibinga
  • P. C. Das
  • S. Seidl

Part of the Developments in Hematology and Immunology book series (DIHI, volume 13)

Table of contents

  1. Front Matter
    Pages I-XIII
  2. Source material

  3. Technology of plasma fractionation

    1. Front Matter
      Pages 41-41
    2. H. G. J. Brummelhuis
      Pages 47-56
    3. P. R. Foster, A. J. Dickson
      Pages 57-65
    4. J. Over, M. P. J. Piët, J. A. Loos, H. P. J. Henrichs, P. J. Hoek, M. A. von Meyenfeldt et al.
      Pages 67-78
    5. S. M. Middleton
      Pages 83-88
    6. F. Haskó, K. Kristóf, M. Salamon, P. Dobó
      Pages 105-114
    7. C. Th. Smit Sibinga, P. C. Das, S. Seidl
      Pages 115-123
  4. Safety aspects

  5. Clinical aspects

    1. Front Matter
      Pages 187-187
    2. S. Seidl
      Pages 189-195
    3. P. C. Das, P. H. M. J. Thijssen, R. L. McShine, C. Th. Smit Sibinga
      Pages 217-222
    4. J. B. Bussel
      Pages 231-235
    5. C. Th. Smit Sibinga, P. C. Das, S. Seidl
      Pages 237-242

About this book

Introduction

Plasma fractionation and blood transfusion are inherently linked. Blood­ bankers need to have a sincere interest in fractionation and purification techniques in order to understand the need for carefully controlled source material collection and initial processing. Developments point to a shift in technology, implementation and application of plasma fractions to be produced, such that early anticipation from both bloodbankers and fractionators in a joint interest and effort are needed. As usual there is good news and bad news. We are referring in that respect to the exciting presentation about the future of bloodbanking. Although the blood donor still plays a major role in bloodbanking, new technologies could terminate the conventional blood transfusion service in the next 20-40 years. Sooner or later DNA technology will play an important role in bloodbanking and bloodbankers will have to deal with cultivated red cells as a replacement of our donor blood. Several fractionation techniques like column chromatography, controlled pore glass chromatography, heparin double cold precipitation technology and polyelectrolite fractionation are available, which may result in better yields for some of the plasma proteins. These techniques are likely to replace in part the old Cohn fractionation in the near future.

Keywords

blood plasma proteins

Editors and affiliations

  • C. Th. Smit Sibinga
    • 1
  • P. C. Das
    • 1
  • S. Seidl
    • 2
  1. 1.Red Cross Blood Bank Groningen-DrentheGroningenThe Netherlands
  2. 2.Red Cross Blood Transfusion Service HessenFrankfurt am MainGermany

Bibliographic information