Renal Stone Disease

Pathogenesis, Prevention, and Treatment

  • Charles Y. C. Pak

Part of the Topics in Renal Medicine book series (TIRM, volume 5)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Neil S. Mandel, Gretchen S. Mandel
    Pages 1-24
  3. Joseph E. Zerwekh
    Pages 25-45
  4. Neil A. Breslau, Khashayar Sakhaee
    Pages 47-84
  5. Laurie Wainer, Vicki A. Resnick, Martin I. Resnick
    Pages 85-120
  6. Linda O. Judge
    Pages 121-142
  7. Glenn M. Preminger, Jean A. Harvey
    Pages 143-164
  8. Charles Y. C. Pak
    Pages 165-199
  9. Charles Y. C. Pak, Beverley V. Adams
    Pages 201-224
  10. John S. Rodman
    Pages 225-251
  11. Donald P. Griffith, Randall B. Meacham
    Pages 253-271
  12. Back Matter
    Pages 273-277

About this book


CHARLES Y. c. PAK Major progress has been made in the pathophysiologic elucidation and management of nephrolithiasis during the past two decades. It is now possible to detect the cause of stone disease in more than 95% of patients, to prevent recurrent formation of stones in the majority of patients, and to remove most existing stones less invasively. The assumption of editorship of this book permits me to indulge in the discussion of this progress from my personal perspective. Three somewhat fortuitous events in my academic career dictated my directing major efforts in stone research. The first event occurred in 1963 when, after having completed medical training, I was faced with two years of military service as a participant of the Berry plan. Choices were limited and disconcerting for someone interested in a research career: a staff physician at a military installation or an indian reservation, or a member of a research team in a state penitentiary. An interesting article by Norman Gershfeld on phospholi­ pid monolayers prompted me to write him seeking a position in his laboratory of Health (NIH) in Bethesda, MD. Partly because of at the National Institutes my rudimentary exposure and publication in surface chemistry, I was offered a position as a staff scientist and a position in the Public Health Service which satisfied the requirements of a military service.


Laboratory chemistry health management nutrition pathogenesis pathophysiology patients physiology prevention public health research therapy training treatment

Editors and affiliations

  • Charles Y. C. Pak
    • 1
  1. 1.Center in Mineral Metabolism and Clinical ResearchUniversity of Texas Health Science Center at DallasDallasUSA

Bibliographic information