Fundamental Problems in Breast Cancer

Proceedings of the Second International Symposium on Fundamental Problems in Breast Cancer Held at Banff, Alberta, Canada April 26–29, 1986

  • Alexander H. G. Paterson
  • Alan W. Lees

Part of the Developments in Oncology book series (DION, volume 51)

Table of contents

  1. Front Matter
    Pages i-xviii
  2. The Natural History and Clinical Significance of Breast Cancer Detected by Imaging Techniques

    1. Front Matter
      Pages 1-1
    2. Laszlo Tabar
      Pages 11-16
    3. M. J. Yaffe, R. M. Nishikawa, A. Fenster
      Pages 17-24
    4. Melvin J. Silverstein, Neal Handel, Robert S. Hoffman, James R. Waisman, Robert J. Rosser, Parvis Gamagami et al.
      Pages 47-57
    5. W. R. Castor, F. I. Jackson, T. Hunt
      Pages 59-68
    6. Melvin J. Silverstein, Parvis Gamagami, Robert J. Rosser, Eugene D. Gierson, William J. Colburn, Neal Handel et al.
      Pages 75-89
    7. Catherine E. de Metz, Arthur T. Porter
      Pages 91-95
    8. L. Holmberg, L. Tabar, H. O. Adami, R. Bergström
      Pages 105-111
    9. R. J. Rosser, M. J. Silverstein, E. D. Gierson, P. Gamagami, W. J. Colburn, N. Handel et al.
      Pages 113-124
  3. Aspects of the Growth and Mechanism of Response of Endocrine Sensitive Breast Cancer

  4. Adjuvant Systemic Therapy: Current Clinical Trials and Aspects of Statistical Evaluation of Adjuvant Chemotherapy

    1. Front Matter
      Pages 199-199
    2. John F. Forbes, Richard Gelber, Aron Goldhirsch
      Pages 201-222
    3. Craig Henderson, Rebecca Gelman
      Pages 229-234
    4. Edward Baral, Ulla Glas, Lars-Erik Rutqvist, Lambert Skoog
      Pages 235-238
  5. Research on Life Quality and the Effect of Local and Systemic Therapy on Quality of Life

    1. Front Matter
      Pages 239-239
    2. E. Bruera, C. Brenneis, M. Michaud, John Hanson, A. H. G. Paterson, R. N. MacDonald
      Pages 241-247
    3. John F. McCaffrey
      Pages 259-263
    4. Maria Koch, John Hanson, Herta Gaedke, Diane Wilson
      Pages 265-272
  6. Laboratory Research Relevant to the Management of Patients with Breast Cancer Over the Next Decade

    1. Front Matter
      Pages 281-281
    2. J. L. Mansi, T. J. Powles, R. C. Coombes
      Pages 299-301
    3. John A. Kanis, Richard E. S. Gray, Graeme Urwin, Shona Murray, Neveen Hamdy
      Pages 303-322
  7. Future Directions in the Assessment, Management, and Treatment of the Patient with Breast Cancer

About this book


The chapters in this book are those presented at the Second International Symposium on Fundamental Problems in Breast Cancer held at Banff, Alberta, April 26-29, 1986. This is, therefore, the second volume in the series of symposia held in the Canadian Rockies. The aim of these symposia is to provide a supportive atmosphere for the development of new concepts as well as for the presentation of high quality scientific data. This is reflected in the chapters presented here. Many of the chapters put forward new hypotheses which will be tested in the clinic or laboratory in the next few years. In choosing the subjects for discourse, we preferred to tackle areas where controversy existed, and in this book we have grouped the chapters around discussion themes. The relative merits of mammography and physical examination in the detection of small lesions within the breast and the natural history of these lesions were important topics at the symposium, and the results of early detection studies will have a major effect on health care costs. We have devoted a large section of this book to this subject. The mechanism of growth and response of endocrine sensitive tumors and current concepts of the statistics and cost-benefit assessment of adjuvant chemotherapy trials comprise two other sections of the book where original and stimulating ideas were presented.


Cancer Screening biopsy carcinoma imaging imaging techniques systemic therapy

Editors and affiliations

  • Alexander H. G. Paterson
    • 1
  • Alan W. Lees
    • 1
  1. 1.Breast UnitCross Cancer InstituteEdmontonCanada

Bibliographic information