Viruses, Immunity, and Mental Disorders

  • Edouard Kurstak
  • Z. J. Lipowski
  • P. V. Morozov

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Viruses and Organic Mental Disorders

    1. Front Matter
      Pages 1-1
    2. Stanley B. Prusiner, Ronald A. Barry, Michael P. McKinley, Carolyn G. Bellinger, Rudolf K. Meyer, Stephen J. DeArmond et al.
      Pages 23-32
    3. R. M. Ridley, H. F. Baker, T. J. Crow
      Pages 33-45
    4. Melvyn J. Ball
      Pages 61-64
    5. Richard J. Loewenstein, David R. Rubinow
      Pages 95-107
  3. Viruses and Functional Mental Disorders

    1. Front Matter
      Pages 123-123
    2. Timothy J. Crow
      Pages 125-134
    3. J. Rajčáni, H. Libíková, J. Smereková, V. Mucha, M. Kúdelová, J. Pogády et al.
      Pages 135-148
    4. Carlo Lorenzo Cazzullo, Domenico Caputo, Laura Bellodi, Cesare Maffei, Pasquale Ferrante, Fernanda Bergamini et al.
      Pages 149-155
    5. Victor M. Vostrikov, Akim I. Oifa
      Pages 157-160
    6. G. R. Taylor, G. I. Carter, T. J. Crow
      Pages 161-171
    7. T. Gotlieb-Stematsky, S. Floru, D. Becker, E. Kritchman, S. Leventon-Kriss
      Pages 173-177
    8. Jay D. Amstrdam, Andrew Winokur, William Dyson, Sibylle Herzog, Francisco Gonzalez, Rudolf Rott et al.
      Pages 179-185
  4. In Vivo and in Vitro Models for Viral Etiology of Neuropsychiatric Diseases

    1. Front Matter
      Pages 187-187
    2. Dennis McFarland, John Hotchin
      Pages 189-198
    3. O. Sorensen, S. Beushausen, M. Coulter-Mackie, R. Adler, S. Dales
      Pages 199-210
    4. Pierre J. Talbot, Robert L. Knobler, Michael J. Buchmeier
      Pages 211-220
    5. Erik Lycke, Bo Svennerholm, Anders Vahlne, Richard J. Ziegler
      Pages 221-226
    6. Henri Tsiang, Rugimar Marcovistz, Patrick Gourmelon
      Pages 235-243
    7. Klaus Koschel, P. Noel Barrett, Roland Metzner, Jutta Zinnheimer
      Pages 245-256
    8. Edward G. Shaskan, John D. Shanley, Lars Oreland, Goran Wadell
      Pages 257-267
  5. Immunity, Interferon, and Psychiatric Disorders

    1. Front Matter
      Pages 269-269
    2. Lynn Eleanor DeLisi
      Pages 271-283
    3. G. I. Kolyaskina, T. P. Sekirina, A. A. Zozulya, S. G. Kushner, M. Ya. Zuzulkovskaya, L. I. Abramova
      Pages 285-294
    4. O. A. Vasiljeva, T. P. Vetlugina, H. Libíková, J. Rajčáni, G. V. Logvinovitch, V. Ya. Semke et al.
      Pages 295-305
    5. Charles A. Kaufmann, Lynn E. DeLisi, E. Fuller Torrey, Susan E. Folstein, William J. Smith
      Pages 307-320
    6. Rohan Ganguli, Bruce Rabin, Usha Raghu, Richard S. Ulrich
      Pages 321-326
    7. Motoe Hirata-Hibi, Motow Oh, Kazuko Miyauchi, Takehiko Tachibana
      Pages 327-341
    8. Joseph R. Calabrese, A. Dale Gulledge, Kurt Hahn, Robert Skwerer, Margaret Kotz, O. P. Schumacher et al.
      Pages 353-362
    9. Ziad Kronfol, Janice Quinn, J. Daniel House, Henry A. Nasrallah
      Pages 363-367
    10. Henry A. Nasrallah, Zuhair K. Ballas, Ziad Kronfol, Suzanne M. Chapman
      Pages 369-372
    11. Ranan Rimón, Antti Ahokas
      Pages 379-382
    12. Hans Werner Moises, Liesel Schindler, Holger Kirchner
      Pages 383-387
  6. Stress and Depression and Susceptibility to Viral Infection, and Psychiatric Aspects

    1. Front Matter
      Pages 389-389
    2. Janice K. Kiecolt-Glaser, Ronald Glaser
      Pages 403-411
    3. Lawrence G. Wilson
      Pages 413-422
    4. J. Hoenig, Susan Abbey
      Pages 423-439
    5. James F. Jones, Bruce D. Miller
      Pages 441-451
  7. Back Matter
    Pages 453-468

About this book


In spite of progress in biomedical research, we know little about the causes, prevention, and treatment of the numerous mental and neurological disorders that afflict up to 15% of all individuals. In the last decade, great advances have been made in the physiopathology of mental and neurological disorders, leading to at least a partial control of Parkinson's disease, epilepsy, certain psychoses, and anxiety syndromes. Despite the fact that an underlying specific neurotransmitter deficiency has been demonstrated in Alzheimer's and Parkinson's diseases, the immune dysfunction and viral hypotheses continue to be attractive for investigators dealing with these degenerative diseases of the aging brain, which afflict 10% of senior citizens. A retrospective epidemiologic study suggests that the encephalitis lethargica and parkinsonism were almost certainly caused by the 1918 influenza virus pandemics. It must be stressed that the etiopathogenesis of many mental disorders is not known, and this ignorance has led to several untenable neurophysiological and biochemical hypotheses. Epidemiologic investigations show a high prevalence of functional psychoses and organic mental disorders. Although many of them are conceptualized as biopsychosocial disorders, recent data indicate that the biological component appears more and more as a major etiologic factor. Among the various biological hypotheses, the viral and im­ munologic concept has become a significant one. In view of recent discoveries in virology and immunity, it becomes clear that viral and immunologic hypotheses should be inves­ tigated more systematically concerning the mechanisms of numerous mental and neu­ rological disorders.


Alzheimer Parkinson Syndrom pandemics prevention virus

Editors and affiliations

  • Edouard Kurstak
    • 1
    • 2
  • Z. J. Lipowski
    • 3
    • 4
  • P. V. Morozov
    • 5
    • 6
  1. 1.Faculty of MedicineUniversity of MontrealMontrealCanada
  2. 2.International Comparative Virology OrganizationMontrealCanada
  3. 3.Department of PsychiatryUniversity of TorontoTorontoCanada
  4. 4.Clarke Institute of PsychiatryTorontoCanada
  5. 5.World Health OrganizationGenevaSwitzerland
  6. 6.Academy of Medical Sciences of the USSRMoscowUSSR

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 1987
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4612-9007-0
  • Online ISBN 978-1-4613-1799-9
  • Buy this book on publisher's site