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Clinical and Molecular Aspects of Neurotropic Virus Infection

  • Donald H. Gilden
  • Howard L. Lipton

Part of the Developments in Medical Virology book series (DIMV, volume 5)

Table of contents

  1. Front Matter
    Pages i-xv
  2. D. W. Trent, J. T. Roehrig, T. F. Tsai
    Pages 1-41
  3. Francisco Gonzalez-Scarano, Neal Nathanson
    Pages 43-68
  4. M. Brinton
    Pages 69-99
  5. Ehud Lavi, Susan R. Weiss
    Pages 101-139
  6. Daniel C. Pevear, Charles J. Pfau
    Pages 141-172
  7. Larry E. Davis
    Pages 173-202
  8. T. R. Moench, R. T. Johnson
    Pages 203-229
  9. Miriam Calenoff, Burk Jubelt, Howard L. Lipton
    Pages 245-268
  10. Betty L. Slagle, Jerry S. Wolinsky
    Pages 303-318
  11. John E. Greenlee
    Pages 319-342
  12. William G. Stroop, J. Richard Baringer
    Pages 343-367
  13. Abbas Vafai, Donald H. Gilden, Zofia Wroblewska
    Pages 369-391
  14. P. G. E. Kennedy, O. Narayan, M. C. Zink, Jay Hess, J. Clements, R. J. Adams
    Pages 393-421
  15. Stanley B. Prusiner, Karen K. Hsiao, Dale E. Bredesen, David T. Kingsbury
    Pages 423-467
  16. Henry F. McFarland, Steven Jacobson
    Pages 469-499
  17. Diane E. Griffin, Thiravat Hemachudha, Richard T. Johnson
    Pages 501-527
  18. Back Matter
    Pages 529-543

About this book

Introduction

In the summer of 1984, both of us were working with Professor Yechiel Becker in the Laboratory for Molecular Virology at the Hebrew University-Hadassah Medical center in Jerusalem. During a discussion about the increasing number of specialized journals and monographs, Dr. Becker pointed out that none covered both the clinical and molecular aspects of neurotropic virus infections, and he urged us to develop such a book with the help of colleagues who were conducting highly-regarded research in their individual areas related to neurotropic viruses. The responses to our request were gratifying, and each contribution provided both a comprehensive clinical description of the neurologic disease produced by a specific virus and an up-to-date review of the current research in the pathogenesis of the disease, with particular attention given to molecular mechanisms. Most, but not all chapters were written by clinical neurologists who applied basic science strategies and methodologies to the question of how neurotropic viruses produce disease. other chapters were written by virologists known for their longstanding commitment and expertise in the analysis of the pathogenesis of neurotropic virus infections. Thus, this unique monograph should be valuable to all clinicians caring for patients with CNS viral diseases and to "neurovirologists" needing an update of the clinical and molecular pathogenesis of neurotropic virus infections. While this monograph was being prepared, a rapidly expanding literature indicated that the human lenteviruses, human immunodeficiency viruses (HIV) and HTLV-1 were highly neurotropic.

Keywords

HIV Nervous System attention central nervous system immunodeficiency infection pathogenesis prions virology virus

Editors and affiliations

  • Donald H. Gilden
    • 1
  • Howard L. Lipton
    • 2
  1. 1.Department of NeurologyUniversity of Colorado Health Sciences CenterDenverUSA
  2. 2.Department of NeurologyNorthwestern University Medical SchoolChicagoUSA

Bibliographic information