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The Molecular Immunology of Complex Carbohydrates

  • Albert M. Wu
  • L. Garry Adams

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 228)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Antibody Specificity, Epitope and Lectinology

  3. Complex Carbohydrates as Antigens

    1. Anthony Herp, Carol Borelli, Albert M. Wu
      Pages 395-435
    2. Sandro Sonnino, Riccardo Ghidoni, Giuliano Gazzotti, Domenico Acquotti, Guido Tettamanti
      Pages 437-464
    3. Albert M. Wu, Neil E. MacKenzie, L. Garry Adams, Roberta Pugh
      Pages 551-576
    4. Hubert Mayer, Joanna Radziejewska-Lebrecht, Stefan Schramek
      Pages 577-591
    5. Hagen Bretting, Gunter Jacobs, Ulrike Knels, Jochen Thiem, Wilfried Konig
      Pages 599-599
  4. Glycoconjugates as Cancer/or Tumor Antigens

    1. Byron Anderson, Lyman E. Davis, Mario Venegas
      Pages 601-656
    2. David Zopf, Gunnar C. Hansson
      Pages 657-676
    3. Tatsuro Irimura, Motowo Nakajima, Takao Yamori, David M. Ota, Karen F. Cleary, Garth L. Nicolson
      Pages 677-704
  5. Structural Analysis of Hapten Moiety of Complex Carbohydrate Antigens

    1. Vernon N. Reinhold, Sitthivet Santikarn
      Pages 727-758
    2. Theodore A. W. Koerner, Robert K. Yu, J. Neel Scarsdale, Peter C. Demou, James H. Prestegard
      Pages 759-784
    3. Blair A. Sowa, Richard P. Crawford, Fred C. Heck, John D. Williams, Albert M. Wu, Katherine A. Kelly et al.
      Pages 815-816
  6. Appendix I: A Guide for Carbohydrate Specificities of Lectins

    1. Front Matter
      Pages 817-817
    2. Albert M. Wu, Shunji Sugii, Anthony Herp
      Pages 819-847
  7. Back Matter
    Pages 849-868

About this book

Introduction

During the past three decades, the sugar moiety of complex carbohydrates has been found to be involved in important interactions of immunological specificity of antigens and to participate in a variety of cellular functions. The long polysaccharide side chains of the lipopolysaccharides on the outer membrane of Gram negative organisms provide surface antigens for differential serodiagnosis. Bacterial surface lectins are important in mediating the attachment of bacteria to host cells in the of infectious diseases. The carbohydrate pathogenesis moieties of cell surface glycoconjugates (glycoproteins and glycolipids) of mammals are the sites for intercellular recognition and for the regulatory molecular interactions such as interaction of complex carbohydrate with hormones or hepatic lectins. The carbohydrate side chains of many complex carbohydrates play essential roles as antigenic determinants b of human blood group ABH, Lea, Le , I, and i activities, as the Forssman specific determinant, and as tumor associated antigenic determinants. Prompted by these and other advances in the field, a Symposium on Molecular Immunology of Complex Carbohydrates was organized as a satellite meeting of the 8th International Glycoconjugate Conference held on September 8- 13, 1985, in Houston, Texas, U. S . A. Many eminent scientists contributed their knowledge at this meeting. The lecture and poster materials of the symposium are contained in this proceeding book, which is divided into four Sections and one Appendix. Section I is entitled Antibody Specificity, Epitope, and Lectinology. Dr. Elvin A.

Keywords

Antigen Colon Oligosaccharid Polysaccharid biochemistry enzymes infectious disease proteins

Editors and affiliations

  • Albert M. Wu
    • 1
  • L. Garry Adams
    • 1
  1. 1.Texas Agricultural Experimental StationTexas A&M UniversityCollege StationUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4613-1663-3
  • Copyright Information Springer-Verlag US 1988
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4612-8923-4
  • Online ISBN 978-1-4613-1663-3
  • Series Print ISSN 0065-2598
  • Buy this book on publisher's site