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Prescribing Hemodialysis

A Guide to Urea Modeling

  • Thomas A. Depner

Part of the Developments in Nephrology book series (DINE, volume 29)

Table of contents

  1. Front Matter
    Pages i-xxiii
  2. Thomas A. Depner
    Pages 1-24
  3. Thomas A. Depner
    Pages 25-37
  4. Thomas A. Depner
    Pages 39-63
  5. Thomas A. Depner
    Pages 65-89
  6. Thomas A. Depner
    Pages 91-126
  7. Thomas A. Depner
    Pages 127-165
  8. Thomas A. Depner
    Pages 167-194
  9. Thomas A. Depner
    Pages 195-224
  10. Thomas A. Depner
    Pages 225-242
  11. Thomas A. Depner
    Pages 243-252
  12. Back Matter
    Pages 253-291

About this book

Introduction

What regulation shall we have for the operation? Shall a man transfuse he knows not what. to correct he knows not what. God knows how (l)? Dr. Henry Stubbs Royal College of Physicians circa 1670 If dialysis therapy were a new phannaceutical product being evaluated by the FDA now, it might not be approved for marketing. The recommended dose, its potential toxicity, the side effects of under-or over-dialysis as well as its efficacy have been the subject of very few studies. The high mortality rate associated with the treatment may raise a few eyebrows. That it is a life-saving modality of treatment is undoubtedly true for more than 100,000 patients in the United States and for more than a million patients world­ wide. Because dialysis has extended the lives of many people by a variable period of time, most nephrologists have "rested on their laurels" and did not vigorously pursue studies to optimize these treatments. But facts have a way of intruding in all our lives and the facts are that the overall mortality rate of dialysis patients in the United States is rising and stands close to 25% per year and is closer to 33% per year for patients between the ages of 65 and 74 (2). These mortality figures are considerably higher for age-adjusted dialysis populations in Europe and particu­ larly in Japan, and certainly for the age-adjusted nonnal population.

Keywords

dialysis kidney physiology

Authors and affiliations

  • Thomas A. Depner
    • 1
  1. 1.University of CaliforniaDavisUSA

Bibliographic information