© 1988

The Bile Acids: Chemistry, Physiology, and Metabolism

Volume 4: Methods and Applications

  • Kenneth D. R. Setchell
  • David Kritchevsky
  • Padmanabhan P. Nair

Table of contents

  1. Front Matter
    Pages i-xix
  2. J. Sjövall, K. D. R. Setchell
    Pages 1-42
  3. Toshio Nambara, Junichi Goto
    Pages 43-64
  4. Stephen Barnes, David N. Kirk
    Pages 65-136
  5. S. E. Ealick, C. E. Bugg
    Pages 137-165
  6. A. M. Lawson, K. D. R. Setchell
    Pages 167-267
  7. A. Roda, E. Roda, D. Festi, C. Colombo
    Pages 269-314
  8. J. Schölmerich, A. Roda, M. DeLuca
    Pages 315-339
  9. Jacqueline Dupont, Pilar A. Garcia, Bernhard Hennig, Nina K. Dodd, Suk Yon Oh, Charles E. Sizer et al.
    Pages 341-372
  10. Nabila Turjman, Padmanabhan P. Nair
    Pages 373-378
  11. G. M. Murphy
    Pages 379-403
  12. Peter Back
    Pages 405-440
  13. K. D. R. Setchell, J. M. Street, J. Sjövall
    Pages 441-570
  14. Back Matter
    Pages 571-582

About this book


Over a decade has elapsed since the last volume in this series was published. At that time we considered that we had comprehensively covered all aspects relating to bile acid chemistry and physiology. However, major strides have been made in our understanding of the physiology and pathophysiology of bile acids, due largely to the great advances which have taken place in analytical technology. As a result, the need to document these advances was felt acutely, and therefore this volume is devoted to methodologies in bile acid analysis and their applications. This volume includes twelve chapters written by prominent scientists in the field of bile acid research. The initial chapter discusses techniques of extraction and isolation of bile acids from biological fluids. It is followed by descriptions of physical methods of analysis and discussions of the way these techniques have been applied in the field of bile acid research. Of practical value is the inclusion of a comprehensive list of spectra obtained for refer­ ences by nuclear magnetic resonance spectroscopy and mass spectrometry . These chapters are followed by reviews of biological methods of immuno­ assay and bioluminescence. Specific applications of these techniques are then addressed in contributions relating to bile acid analysis of tissue, serum, urine, and feces. With this integrated approach we have attempted to provide a volume which represents a comprehensive review of the analytical field of bile acids, while also serving as a useful reference book for those workers involved in bile acid analysis.


Colon Lipid cancer chemistry enzyme enzymes hepatobiliary diseases immunology liver liver disease metabolism protein synthesis

Editors and affiliations

  • Kenneth D. R. Setchell
    • 1
  • David Kritchevsky
    • 2
  • Padmanabhan P. Nair
    • 3
    • 4
  1. 1.Children’s Hospital Medical CenterCincinnatiUSA
  2. 2.The Wistar InstitutePhiladelphiaUSA
  3. 3.Lipid Nutrition LaboratoryBeltsville Human Nutrition Research Center, ARS, USDABeltsvilleUSA
  4. 4.The Johns Hopkins University School of Hygiene and Public HealthBaltimoreUSA

Bibliographic information

  • Book Title The Bile Acids: Chemistry, Physiology, and Metabolism
  • Book Subtitle Volume 4: Methods and Applications
  • Editors K.D.R. Setchell
    David Kritchevsky
    Padmanabhan P. Nair
  • DOI
  • Copyright Information Springer-Verlag US 1988
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-0-306-42622-3
  • Softcover ISBN 978-1-4612-8236-5
  • eBook ISBN 978-1-4613-0901-7
  • Edition Number 1
  • Number of Pages , 604
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Gastroenterology
    Biochemistry, general
  • Buy this book on publisher's site