Neuropsychopharmacology of the Trace Amines

Experimental and Clinical Aspects

  • A. A. Boulton
  • L. Maitre
  • P. R. Bieck
  • P. Riederer

Table of contents

  1. Front Matter
    Pages i-xv
  2. Introduction

    1. Front Matter
      Pages 1-1
  3. Neuropsychopharmacology

    1. Front Matter
      Pages 13-13
    2. Invited Communications

      1. R. Ortmann, M. Schaub, P. C. Waldmeier
        Pages 63-74
      2. A. V. Juorio, A. J. Greenshaw, A. A. Boulton
        Pages 87-99
      3. P. L. Wood, L. L. Martin, C. A. Altar
        Pages 101-114
      4. Rudy Susilo, Hans Rommelspacher
        Pages 141-151
      5. J. C. David, J. Delacour, J. F. Coulon, C. Guenaire
        Pages 153-160
      6. Hiroyasu Kinemuchi, Yuichiro Arai, Yoshie Toyoshima, Takeshi Tadano, Kensuke Kisara
        Pages 161-171
    3. Free Communications

      1. Ronald T. Coutts, Glen B. Baker, Adil J. Nazarali, Tadimeti S. Rao, Ronald G. Micetich, T. W. Eric Hall
        Pages 175-180

About this book

Introduction

A probable neurobiological role for the trace amines began to emerge as soon as techniques sufficiently sophisticated to detect them were developed. Techniques for quantitative analyses included radioenzymatic procedures and, more recently, HPlC-EC and auto­ mated GC-MS. The methods are applied after separation of the sub­ stances to be analyzed and after their purification by physicochemical procedures that are becoming more and more efficient. The identification and quantitative analysis of minute amounts of trace amines in biological fluids or tissues is in itself a remarkable technological achievement. The enormous task that several teams of research workers have set themselves is to investigate the origin of the trace amines, to understand their metabolism, and to discover whether or not they possess an important biological role. The 2nd Trace Amines Symposium at Weitenburg Castle near Tubingen from the 15th to the 19th May 1985 was held to gain a somewhat clearer insight into the present state of knowledge. Since the first meeting in 1983 our knowledge has increased and interest is deepening. Hence the idea proposed at that first meeting, of organizing similar gather­ ings at regular intervals, has come to fruition. Covered in the Neuropsychopharmacology section of this book are studiesof the effects of certain trace amines on different forms of be­ havior, on neurotransmission mediated by . the classical neuro­ transmitters, on their biosynthesis or on catabolism, on their possible occurrence as a result of alternative metabolic pathways for the amino acids, and in some instances their neuroanatomical distributions.

Keywords

Monoaminoxidase-Hemmer Nervous System Psychopharmacology Syndrom amphetamine attention attention deficit disorder (ADD) behavior catecholamines dopamine neurons

Editors and affiliations

  • A. A. Boulton
    • 1
  • L. Maitre
    • 2
  • P. R. Bieck
    • 3
  • P. Riederer
    • 4
  1. 1.Psychiatric Research Division, Saskatchewan HealthUniversity of SaskatchewanSaskatoonCanada
  2. 2.Research DepartmentCIBA-GEIGY AGBaselSwitzerland
  3. 3.Human Pharmacology InstituteCIBA-GEIGY GmbHTübingenFederal Republic of Germany
  4. 4.Ludwig-ßoltzmann Institut für klinische NeurobiologieKrankenhaus Wien-LainzWienAustria

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4612-5010-4
  • Copyright Information Humana Press 1985
  • Publisher Name Humana Press
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4612-9397-2
  • Online ISBN 978-1-4612-5010-4
  • About this book