The Brain as an Endocrine Organ

  • Margo Panush Cohen
  • Piero P. Foà

Part of the Endocrinology and Metabolism book series (EAM, volume 3)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Lynnette K. Nieman, D. Lynn Loriaux, George P. Chrousos
    Pages 14-45
  3. Mary Ann Marrazzi, Elliot D. Luby
    Pages 46-95
  4. Hideo Sasaki, Seijiro Marubashi, Yoshikazu Yawata, Keiichi Yamatani, Makoto Tominaga, Tadashi Katagiri
    Pages 150-192
  5. Back Matter
    Pages 251-269

About this book


In the middle of the 17th century, the great French philosopher Rene Descartes wrote (L'Homme, J. Le Gras, Paris, 1669) that a suitable stimulation of the brain results in two types of "movements": exterior movements, designed to seek desirable ends and to avoid undesirable or harmful ones and interior movements or "passions" which through the release of "animal spirits" regulate the heart, the liver, and other organs. When it appears appropriate to meet a threat with force, the passion of rage causes the release of strong spirits, whereas when avoidance appears to be the better choice, the passion of fear causes the brain to release weak spirits. We do not know what influence, if any, Descartes had on the thinking of Walter B. Cannon (Bodily Changes in Pain, Hunger, Fear and Rage, Appleton and Co. , New York, 1920), of Hans Selye (The Story of the Adaptation Syndrome, Acta, Inc. , Montreal, 1952), ofG. W. Harris or of R. Guillemin (Hypothalamic-Hypophysial Interrelationships. A Sym­ posium. c. c. Thomas, Springfield, 1956), but it is interesting to reflect upon the durable value of great ideas which constantly resurface even if modified by other ideas and by new techniques, as if propelled by a preordained intellectual imperative.


Anorexia nervosa Gonadotropin Nervous System Syndrom adenosine brain clinical application hormones insulin metabolism neurobiology neuropeptides physiology thinking tissue

Editors and affiliations

  • Margo Panush Cohen
    • 1
    • 2
  • Piero P. Foà
    • 3
    • 4
    • 5
  1. 1.University of Medicine and Dentistry of New JerseyNewarkUSA
  2. 2.Institute for Metabolic ResearchUniversity City Science CenterPhiladelphiaUSA
  3. 3.Wayne State UniversityDetroitUSA
  4. 4.Department of ResearchSinai HospitalDetroitUSA
  5. 5.West BloomfieldUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag New York 1989
  • Publisher Name Springer, New York, NY
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4612-8118-4
  • Online ISBN 978-1-4612-3480-7
  • Series Print ISSN 0938-040X
  • Buy this book on publisher's site