Linear Mixed Models in Practice

A SAS-Oriented Approach

  • Geert Verbeke
  • Geert Molenberghs

Part of the Lecture Notes in Statistics book series (LNS, volume 126)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Geert Molenberghs, Geert Verbeke
    Pages 1-9
  3. Luc Duchateau, Paul Janssen
    Pages 11-61
  4. Geert Verbeke
    Pages 63-153
  5. Geert Verbeke, Geert Molenberghs
    Pages 155-189
  6. Geert Molenberghs, Luc Bijnens, David Shaw
    Pages 191-274
  7. Back Matter
    Pages 275-308

About this book


The dissemination of the MIXED procedure in SAS has provided a whole class of statistical models for routine use. We believe that both the ideas be­ hind the techniques and their implementation in SAS are not at all straight­ forward and users from various applied backgrounds, including the phar­ maceutical industry, have experienced difficulties in using the procedure effectively. Courses and consultancy on PROC MIXED have been in great demand in recent years, illustrating the clear need for resource material to aid the user. This book is intended as a contribution to bridging this gap. We hope the book will be of value to a wide audience, including applied statisticians and many biomedical researchers, particularly in the pharma­ ceutical industry, medical and public health research organizations, con­ tract research organizations, and academic departments. This implies that our book is explanatory rather than research oriented and that it empha­ sizes practice rather than mathematical rigor. In this respect, clear guidance and advice on practical issues are the main focus of the text. Nevertheless, this does not imply that more advanced topics have been avoided. Sections containing material of a deeper level have been sign posted by means of an asterisk.


SAS data analysis fitting likelihood statistics

Authors and affiliations

  • Geert Verbeke
    • 1
  • Geert Molenberghs
    • 2
  1. 1.Biostatistical Centre for Clinical TrialsKatholieke Universiteit LeuvenLeuvenBelgium
  2. 2.BiostatisticsLimburghs Universitair CentrumDiepenbeekBelgium

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag New York 1997
  • Publisher Name Springer, New York, NY
  • eBook Packages Springer Book Archive
  • Print ISBN 978-0-387-98222-9
  • Online ISBN 978-1-4612-2294-1
  • Series Print ISSN 0930-0325
  • Buy this book on publisher's site