Living Morphogenesis of the Heart

  • María Victoria de la Cruz
  • Roger R. Markwald

Part of the Cardiovascular Molecular Morphogenesis book series (CARDMM)

Table of contents

About this book


The overall scope of this new series will be to evolve an understanding of the genetic basis of (1) how early mesoderm commits to cells of a heart lineage that progres­ sively and irreversibly assemble into a segmented, primary heart tube that can be remodeled into a four-chambered organ, and (2) how blood vessels are derived and assembled both in the heart and in the body. Our central aim is to establish a four-dimensional, spatiotemporal foundation for the heart and blood vessels that can be genetically dissected for function and mechanism. Since Robert DeHaan's seminal chapter "Morphogenesis of the Vertebrate Heart" published in Organogenesis (Holt Rinehart & Winston, NY) in 1965, there have been surprisingly few books devoted to the subject of cardiovascular morpho­ genesis, despite the enormous growth of interest that occurred nationally and internationally. Most writings on the subject have been scholarly compilations of the proceedings of major national or international symposia or muItiauthored volumes, often without a specific theme. What is missing are the unifying concepts that can make sense out of a burgeoning database of facts. The Editorial Board of this new series believes the time has come for a book series dedicated to cardiovas­ cular morphogenesis that will serve not only as an important archival and didactic reference source for those who have recently come into the field but also as a guide to the evolution of a field that is clearly coming of age.


Developmental Biology biology cardiology cardiovascular congenital heart disease diseases growth heart

Editors and affiliations

  • María Victoria de la Cruz
    • 1
  • Roger R. Markwald
    • 2
  1. 1.Departamento de Biología del Desarrollo y TeratogénesisHospital Infantil de México “Federico Gómez”MéxicoMéxico
  2. 2.Department of Cell Biology and AnatomyMedical University of South CarolinaCharlestonUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 1998
  • Publisher Name Birkhäuser, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4612-7283-0
  • Online ISBN 978-1-4612-1788-6
  • Buy this book on publisher's site