Cell Death and Diseases of the Nervous System

  • Vassilis E. Koliatsos
  • Rajiv R. Ratan

Table of contents

  1. Front Matter
    Pages i-xxi
  2. Definitions—Cellular and Molecular Mechanisms

    1. Front Matter
      Pages 1-1
    2. Peter G. H. Clarke
      Pages 3-28
    3. Randall N. Pittman, Conrad A. Messam, Jason C. Mills
      Pages 29-43
    4. Marcel Leist, Pierluigi Nicotera
      Pages 69-90
    5. Anthony Rosen, Livia Casciola-Rosen
      Pages 91-101
    6. Robert S. Freeman
      Pages 103-119
  3. Animal Models

    1. Front Matter
      Pages 121-121
    2. Dewey Royal, Monica Driscoll
      Pages 123-144
    3. Jeffrey L. Elliott, William D. Snider
      Pages 181-196
    4. John W. Olney, Masahiko J. Ishimaru
      Pages 197-219
    5. Elizabeth O’Hearn, Mark E. Molliver
      Pages 221-245
  4. Nerve Cell Death in Human Diseases

    1. Front Matter
      Pages 247-247
    2. Brian G. Fuller, Vilhelm Bohr
      Pages 249-274
    3. Kevin M. Flanigan, Rajiv R. Ratan
      Pages 275-293
    4. J. Marie Hardwick, David N. Irani, Diane E. Griffin
      Pages 295-323
    5. David R. Borchelt
      Pages 325-342
    6. Cheolsu Shin, Ki-Hyeong Lee
      Pages 361-378
    7. W. Dalton Dietrich
      Pages 379-399
    8. Stephen A. Back, Joseph J. Volpe
      Pages 401-427
    9. Bruce A. Rabin, David R. Borchelt
      Pages 429-443
    10. Katherine A. Wood
      Pages 445-458
    11. Robert E. Burke
      Pages 459-475
    12. Christopher A. Ross, Mark W. Becher, Vassilis E. Koliatsos
      Pages 477-496
    13. Harris A. Gelbard
      Pages 511-519
    14. Jean Lud Cadet
      Pages 521-526
    15. Steven E. Arnold
      Pages 527-541
  5. Approaches in Treating Nerve Cell Death

  6. Back Matter
    Pages 667-683

About this book


Written by pioneers in the field, Cell Death and Diseases of the Nervous System captures all the important classic and new research on neuronal injury and cell death and the application of these results to the treatment of a wide range of neurological and neuropsychiatric illness. The outcome is a unique integration of cellular and molecular insights, clinical knowledge, and therapeutic experience. As the chapters move back and forth from the basic to the clinical level, exciting possibilities emerge for finding therapeutic approaches to neurological illness based on a new understanding of fundamental processes. Extensive cross-referencing allows easy navigation between chapters and different points of view.

Cell Death and Diseases of the Nervous System provides a concise summary of current neurological knowledge from the perspective of the basic disease mechanisms involved in neuronal injury and death. In an era of increasing specialization, this book offers an authoritative integration and unique cross-fertilization for all those seeking to better understand and treat neurological illness.


Alzheimer Nervous System Parkinson alzheimer's disease brain neurons schizophrenia trauma

Editors and affiliations

  • Vassilis E. Koliatsos
    • 1
  • Rajiv R. Ratan
    • 2
  1. 1.The Johns Hopkins University School of MedicineBaltimoreUSA
  2. 2.Beth Israel Deaconess Medical Center and Harvard Medical SchoolBostonUSA

Bibliographic information