Blood Pressure and Arterial Wall Mechanics in Cardiovascular Diseases

  • Michel E. Safar
  • Michael F. O'Rourke
  • Edward D. Frohlich

Table of contents

  1. Front Matter
    Pages i-xx
  2. Blood Pressure: Basic Concepts of Steady and Pulsatile Arterial Hemodynamics

    1. Front Matter
      Pages 1-1
    2. Harry A. J. Struijker-Boudier
      Pages 15-21
    3. Luc M. Van Bortel, Tine De Backer, Patrick Segers
      Pages 23-35
    4. Julio A. Chirinos, Patrick Segers
      Pages 37-50
    5. Pierre Boutouyrie, Laurent Macron, Elie Mousseaux, Stéphane Laurent
      Pages 51-62
    6. Patrick Lacolley, Simon N. Thornton, Yvonnick Bezie
      Pages 63-74
    7. Athanase Benetos, Abraham Aviv, Patrick Lacolley, Michel E. Safar, Véronique Regnault
      Pages 83-94
  3. Blood Pressure and Sodium Balance: Pathophysiological Mechanisms and Cardiovascular Risk

    1. Front Matter
      Pages 95-95
    2. Ernesto L. Schiffrin, Alain Tedgui, Stephanie Lehoux
      Pages 97-106
    3. Robinson Joannidès, Jérémy Bellien, Christian Thuillez
      Pages 107-121
    4. Jean-Jacques Mourad, Jean-Sébastien Silvestre, Bernard I. Lévy
      Pages 123-136
    5. Majd AlGhatrif, Edward G. Lakatta
      Pages 137-153
    6. Gianfranco Parati, Paolo Salvi
      Pages 163-173
    7. Jing Wu, David G. Harrison
      Pages 175-191
    8. Scott L. Hummel
      Pages 193-203
  4. Hypertension: Evaluation of Cardiovascular Risk and Organ Damage

    1. Front Matter
      Pages 241-241
    2. Stanley S. Franklin, Carmel M. McEniery, John R. Cockcroft, Ian B. Wilkinson
      Pages 243-256
    3. Stéphane Laurent, Pierre Boutouyrie, Francesco Mattace Raso
      Pages 257-266
    4. Alberto P. Avolio, Mark Butlin, Isabella Tan
      Pages 267-279
    5. Alberto P. Avolio, Mark Butlin, Athanase D. Protogerou
      Pages 281-295
    6. Charalambos Vlachopoulos, Dimitrios Terentes-Printzios, Kenji Takazawa, Christodoulos Stefanadis
      Pages 321-338
    7. Marie Briet, Michel Delahousse, Gérard London, Stéphane Laurent, Pierre Boutouyrie
      Pages 339-350
    8. Sola Aoun Bahous, Serge Korjian, Yazan Daaboul, Jacques Blacher, Michel E. Safar
      Pages 351-361
    9. Piotr Jankowski, Jacques Blacher, Thomas Weber
      Pages 363-374
  5. Clinical Involvement: Role of Age, Sex, Inflammatory and Metabolic Alterations

    1. Front Matter
      Pages 375-375
    2. Athanase Benetos, Sylvie Gautier, Michel E. Safar
      Pages 377-386
    3. Athanase Benetos, Ghassan Watfa, Paolo Salvi, Patrick Lacolley
      Pages 387-395
    4. Harold Smulyan, Bruno Pannier
      Pages 397-408
    5. Isabel Ferreira, Roel J. J. van de Laar, Coen D. A. Stehouwer
      Pages 409-422
    6. Guanghong Jia, Annayya R. Aroor, Gerald A. Meininger, James R. Sowers
      Pages 423-434
    7. Kaisa M. Mäki-Petäjä, Carmel M. McEniery, Stanley S. Franklin, Ian B. Wilkinson
      Pages 435-444
  6. Stratifications of Cardiovascular Risk and Therapeutic Consequences on Arterial Stiffness and Wave Reflections

    1. Front Matter
      Pages 445-445
    2. Yumei Gu, Lucas S. Aparicio, Yanping Liu, Kei Asayama, Tine W. Hansen, Teemu J. Niiranen et al.
      Pages 447-457
    3. Yi Zhang, Davide Agnoletti, Alexandra Yannoutsos, Michel E. Safar, Jacques Blacher
      Pages 495-508
    4. Xiong J. Jiang, Michael F. O’Rourke
      Pages 509-518
    5. Athanase D. Protogerou, Michel E. Safar, Gerard E. Plante, Jacques Blacher
      Pages 519-529

About this book


In cardiovascular prevention, there has traditionally been a small number of cardiovascular risk factors to evaluate and manage, such as hypertension, diabetes, hyperlipidemia and smoking. Recently, it has been recognized that new mechanical factors should be identified, and specifically involves pulsatile arterial hemodynamic parameters, such as arterial stiffness, pulse pressure and, to a lesser extent, augmentation index and pulse pressure amplification.​


Blood Pressure and Arterial Wall Mechanics in Cardiovascular Diseases has been written to facilitate understanding of these new concepts regarding bleed pressure and cardiac risk, and prepare the reader for the considerable evolution of the topic in the years to come. Much has been learned already regarding the management of these patients, and this book presents extensive data on the techniques needed to maximize their outcomes.​


arterial stiffness cardiovascular disease prevention hemodynamics pulsatile arterial hemodynamics pulse pressure

Editors and affiliations

  • Michel E. Safar
    • 1
  • Michael F. O'Rourke
    • 2
  • Edward D. Frohlich
    • 3
  1. 1.Hôtel-Dieu Hospital Diagnosis and Therapeutics CenterParis Descartes UniversityParisFrance
  2. 2.St Vincent Clinic and Hospital, University of New South Wales, Victor Chang Cardiac Research InstituteDarlinghurst, SydneyAustralia
  3. 3.Department of CardiologyOchsner Clinic FoundationNew OrleansUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag London 2014
  • Publisher Name Springer, London
  • eBook Packages Medicine
  • Print ISBN 978-1-4471-5197-5
  • Online ISBN 978-1-4471-5198-2
  • Buy this book on publisher's site