Electrical Diseases of the Heart

Volume 1: Basic Foundations and Primary Electrical Diseases

  • Ihor Gussak
  • Charles Antzelevitch

Table of contents

  1. Front Matter
    Pages i-xxi
  2. Basic Fundamentals of Normal and Abnormal Cardiac Electrical Activity

    1. Front Matter
      Pages 1-1
    2. Isabelle Baró, Denis Escande, Sophie Demolombe
      Pages 7-24
    3. Alex V. Postma, Vincent M. Christoffels, Antoon F. M. Moorman
      Pages 25-45
    4. Cristina Basso, Siew Yen Ho, Stefania Rizzo, Gaetano Thiene
      Pages 47-71
    5. Richard L. Verrier, Alex Tan
      Pages 73-92
    6. Charles Antzelevitch, Alexander Burashnikov
      Pages 93-128
    7. Shingo Murakami, Yoshihisa Kurachi
      Pages 129-140
    8. Alexander Burashnikov, Charles Antzelevitch
      Pages 141-156
    9. Sridharan Rajamani, John C. Shryock, Luiz Belardinelli
      Pages 177-191
    10. Yuka Mizusawa, Arthur A. M. Wilde, Hanno L. Tan
      Pages 193-207
    11. Yanfei Ruan, Raffaella Bloise, Carlo Napolitano, Silvia G. Priori
      Pages 209-217
    12. Mitsunori Maruyama, Shengmei Zhou, Gyo-Seung Hwang, Su-Kiat Chua, Po-Cheng Chang, Shien-Fong Lin et al.
      Pages 219-232
    13. Kevin J. Sampson, Robert S. Kass
      Pages 233-244
    14. Alexey E. Alekseev, Santiago Reyes, Satsuki Yamada, Sungjo Park, D. Kent Arrell, Garvan C. Kane et al.
      Pages 245-258
    15. Hai Xia Zhang, Jonathan R. Silva, Colin G. Nichols
      Pages 259-279
    16. Sameer Ather, Xander H. T. Wehrens
      Pages 281-297
    17. Matteo Vatta
      Pages 299-315
    18. Mahek Mirza, Win-Kuang Shen, Arshad Jahangir
      Pages 317-332
    19. Philippe Comtois, Brett Burstein, Stanley Nattel
      Pages 333-352
    20. Fadi G. Akar, Gordon F. Tomaselli
      Pages 369-386
    21. Vincent J. A. Bourgonje, Toon A. B. van Veen, Marc A. Vos
      Pages 387-398
    22. Richard B. Robinson, Peter R. Brink, Ira S. Cohen, Michael R. Rosen
      Pages 399-414
  3. Heritable Arrhythmogenic Channelopathies, Primary Electrical Diseases, and Sudden Cardiac Death

    1. Front Matter
      Pages 435-435
    2. David J. Tester, Peter J. Schwartz, Michael J. Ackerman
      Pages 439-468
    3. Paola G. Meregalli, Hanno L. Tan, Arthur A. M. Wilde
      Pages 469-495
    4. Charles Antzelevitch, Sami Viskin
      Pages 497-536
    5. Nicolas Derval, Frédéric Sacher, Ashok Shah, Sébastien Knecht, Mélèze Hocini, Pierre Jaïs et al.
      Pages 537-550
    6. Nian Liu, Carlo Napolitano, Silvia G. Priori
      Pages 551-560
    7. Martin Tristani-Firouzi, Susan P. Etheridge
      Pages 561-567
    8. Preben Bjerregaard, Ihor Gussak
      Pages 569-581
    9. Jean-Jacques Schott, Flavien Charpentier, Hervé Le Marec
      Pages 583-603
    10. Michiel Rienstra, J. Peter van Tintelen, Rob A. Vermond, Bas A. Schoonderwoerd, Ans C. P. Wiesfeld, Isabelle C. van Gelder
      Pages 605-627
    11. Sami Viskin, Arnon Adler, Bernard Belhassen
      Pages 629-646
  4. Back Matter
    Pages 647-659

About this book


The past two decades have witnessed an explosion of knowledge and radical changes in our understanding of the molecular, ionic, genetic, and pharmacologic basis of electrical diseases of the heart. Electrical diseases of the heart are heritable arrhythmogenic clinical entities that may share common clinical and genetic features, yet may be distinctly different in their genesis, prognosis, and management. Notably, both congenital and acquired electrical diseases of the heart are receiving increased recognition as a result of important advances in genetic analysis.


In this second edition of Electrical Diseases of the Heart, the Editors’ goal has been to embrace and highlight the explosion of knowledge that our field has witnessed since the publication of the first edition.  The approach continues to be one of bridging basic and clinical science in an attempt to advance meaningfully our understanding of heart disease and identify the knowledge gaps that exist. This volume covers the basic foundations and primary electrical diseases and with the companion volume provides the latest developments in the field of experimental and clinical cardiac electrophysiology, genetics, pharmacology and interventional therapies of various clinical arrhythmogenic entities.


Residents, fellows and physicians in cardiology and electrophysiology will gain valuable insight into the latest developments in the field of cardiac electrophysiology and clinical electrocardiology by reading this book, including expert review of the genetic and epidemiologic considerations, diagnostic and therapeutic modalities of the newly discovered clinical syndromes and electrocardiographic phenomena, and their correlation with the most recent advances in the basic science.


Arrhythmia Atrial Fibrillation Brugada syndrome Cardiac electrophysiology Defibrillation Ventricular Fibrillation

Editors and affiliations

  • Ihor Gussak
    • 1
  • Charles Antzelevitch
    • 2
  1. 1., Department of Internal MedicineUMDNJ-RWJ Medical SchoolNew BrunswickUSA
  2. 2., Gordon K. Moe ScholarMasonic Medical Research LaboratoryUticaUSA

Bibliographic information