Book 2014

Engineering in Translational Medicine

Editors:

ISBN: 978-1-4471-4371-0 (Print) 978-1-4471-4372-7 (Online)

Table of contents (35 chapters)

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  1. Front Matter

    Pages i-xix

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    Chapter

    Pages 1-16

    Engineering in Translational Medicine: An Introduction

  3. Cell and Tissue Engineering

    1. Front Matter

      Pages 17-17

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      Chapter

      Pages 19-69

      Stem Cells: The Holy Grail of Regenerative Medicine

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      Chapter

      Pages 71-101

      Engineering T Cells to Target Tumor Cells

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      Chapter

      Pages 103-131

      Engineering Biomaterials for Anchorage-Dependent and Non-anchorage-Dependent Therapeutic Cell Delivery in Translational Medicine

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      Chapter

      Pages 133-153

      Tissue Engineering Applications for Peripheral Nerve Repair

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      Chapter

      Pages 155-182

      Structure, Function, and Development of Blood Vessels: Lessons for Tissue Engineering

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      Chapter

      Pages 183-200

      Engineering Gene-Activated Matrices for the Repair of Articular Cartilage Defect

  4. Genetic and Protein Engineering

    1. Front Matter

      Pages 201-201

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      Chapter

      Pages 203-231

      Engineering Luciferases for Assays and Imaging

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      Chapter

      Pages 233-256

      Engineered Split Reporter Systems for Molecular Imaging of Protein–Protein Interactions in Living Subjects

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      Chapter

      Pages 257-300

      Engineering Aspects of Bioluminescence Resonance Energy Transfer Systems

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      Chapter

      Pages 301-316

      Antibody Engineering in Translational Medicine

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      Chapter

      Pages 317-342

      Engineered Affibodies in Translational Medicine

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      Chapter

      Pages 343-364

      Alternative Protein Scaffolds for Molecular Imaging and Therapy

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      Chapter

      Pages 365-396

      Engineering Multivalent and Multispecific Protein Therapeutics

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      Chapter

      Pages 397-426

      Engineering Aptamers for Biomedical Applications: Part I

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      Chapter

      Pages 427-447

      Engineering Aptamers for Biomedical Applications: Part II

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      Chapter

      Pages 449-471

      Engineering DNA Vaccines for Cancer Therapy

  5. Nanoengineering

    1. Front Matter

      Pages 473-473

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      Chapter

      Pages 475-512

      Multifunctional Nanoscale Delivery Systems for Nucleic Acids

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      Chapter

      Pages 513-534

      Engineering Nanomaterials for Biosensors and Therapeutics

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      Chapter

      Pages 535-566

      Engineering Fluorescent Nanoparticles for Biomedical Applications

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