Human Fetal Tissue Transplantation

  • Niranjan Bhattacharya
  • Phillip Stubblefield

Table of contents

  1. Front Matter
    Pages i-xxix
  2. The Ideas Behind This Book

    1. Front Matter
      Pages 1-1
    2. Niranjan Bhattacharya, Phillip Stubblefield
      Pages 3-13
  3. Basic Science and the Unique Aspect of Fetal Growth and Maturation

    1. Front Matter
      Pages 25-25
    2. Peter Hollands
      Pages 27-46
    3. Yasuyuki Sakai, Jinlan Jiang, Sanshiro Hanada, Hongyug Huang, Takeshi Katsuda, Nobuhiko Kojima et al.
      Pages 47-63
    4. Harris Pratsinis, Andreas A. Armatas†, Dimitris Kletsas
      Pages 65-77
    5. Ines Silva, Cody A. Koch, Raymond J. Lynch, Jeffrey L. Platt
      Pages 79-85
    6. M. L. Weiss, Yelica López, K. R. McIntosh
      Pages 87-105
    7. Maria P. De Miguel, Jon Schoorlemmer, Ignacio Garcia-Tuñón
      Pages 107-119
    8. Oren Pleniceanu, Benjamin Dekel
      Pages 121-140
  4. Fetal Cell Transplant Experiments in Animal and Human Systems

    1. Front Matter
      Pages 159-159
    2. Carolyn Troeger, Irina Perahud, Eva Visca, Wolfgang Holzgreve
      Pages 161-168
    3. Amar Nijagal, Tippi C. MacKenzie
      Pages 169-175
    4. Nathalie Hirt-Burri, Lee Ann Applegate
      Pages 185-192
    5. Yasushi Kondo, Tsuyoshi Okuno, Sayaka Asari, Shin-ichi Muramatsu
      Pages 193-203

About this book

Introduction

Over the past decade there have been major advances in the field of regenerative medicine with the promise to bring to reality, cures for debilitating diseases such as diabetes, heart failure, and Parkinson’s disease. Cellular products from a variety of sources are being evaluated for their ability to replace damaged tissue.

Fetal tissues consist of stem cells and progenitor cells which have undergone initial commitment with varying states of differentiation. Stem cells from fetal tissues may also have a greater proliferative potential than their adult counterparts. In addition, fetal derived stem and progenitor cells are immunologically naive and some sources of fetal cells, eg cord blood, have been shown to be capable of crossing greater HLA mismatching resulting in less rejection and decreased immune mediated toxicities. Given the increasing focus on HES and advances in our basic knowledge of regenerative medicine it is an appropriate time to review the biology and use of fetal tissues.

Human Fetal Tissue Transplantation is a timely publication that provides details of many aspects of the potential use of fetal tissues for therapeutic applications. As many tissues are wasted on a daily basis it appropriate to raise discussion on how to maximize access to discard tissue and at the same time engage in discussion of the ethics associated with fetal tissue procurement and clinical use.

Editors and affiliations

  • Niranjan Bhattacharya
    • 1
  • Phillip Stubblefield
    • 2
  1. 1.KolkataIndia
  2. 2.Dept. Obstetrics & GynaecologyBoston University Medical CentreBostonUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4471-4171-6
  • Copyright Information Springer-Verlag London 2013
  • Publisher Name Springer, London
  • eBook Packages Medicine
  • Print ISBN 978-1-4471-4170-9
  • Online ISBN 978-1-4471-4171-6
  • About this book