Diffuse Low-Grade Gliomas in Adults

Natural History, Interaction with the Brain, and New Individualized Therapeutic Strategies

  • Hugues Duffau

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Epidemiology and Classification

  3. Basic Science and Experimental Research in DLGG

    1. Front Matter
      Pages 73-73
    2. Pierre-Olivier Guichet, Jean-Philippe Hugnot
      Pages 75-89
    3. Nicholas F. Marko, Robert J. Weil
      Pages 99-115
    4. A. M. J. Gerth, R. F. Deighton, J. McCulloch, Ian R. Whittle
      Pages 117-136
    5. Daniela Cesselli, Antonio Paolo Beltrami, Anja Pucer, Evgenia Bourkoula, Tamara Ius, Marco Vindigni et al.
      Pages 137-163
    6. Rolf Bjerkvig, Sébastien Bougnaud, Simone P. Niclou
      Pages 165-175
  4. Clinical Aspects and Diagnostic Imaging

    1. Front Matter
      Pages 177-177
    2. Juan Torres-Reveron, Joseph M. Piepmeier, Kevin P. Becker
      Pages 179-188
    3. Anja Smits
      Pages 189-203
    4. Martin J. B. Taphoorn
      Pages 205-217
    5. Karl-Josef Langen, Frank Willi Floeth, Michael Sabel, Norbert Galldiks
      Pages 235-248
    6. Emmanuel Mandonnet
      Pages 249-262
  5. Natural History and Spontaneous Prognostic Factors

    1. Front Matter
      Pages 263-263
    2. Roberta Rudà, Luca Bertero, Riccardo Soffietti
      Pages 265-275
  6. Functional Assessment and Interaction with the Brain

    1. Front Matter
      Pages 277-277
    2. Sylvie Moritz-Gasser, Guillaume Herbet
      Pages 279-299
  7. New Insights into the Therapeutic Strategies for DLGG

    1. Front Matter
      Pages 357-357
    2. Luc Taillandier
      Pages 401-422
    3. Hugues Duffau, Luc Taillandier
      Pages 435-443
  8. Prospects

    1. Front Matter
      Pages 445-445
    2. Emmanuel Mandonnet
      Pages 447-455
    3. Emmanuel Mandonnet, Luc Bauchet, Luc Taillandier, Hugues Duffau
      Pages 457-462
    4. Guillaume Herbet, Sylvie Moritz-Gasser
      Pages 463-473
    5. Catherine Gozé, Luc Taillandier, Valérie Rigau, Luc Bauchet, Hugues Duffau
      Pages 481-491
  9. Back Matter
    Pages 493-502

About this book


The biology, behavior and management of diffuse low-grade gliomas (DLGG) in adults have been matters of controversy for many decades.  However, recent technical and conceptual advances in genetics, imaging and treatments have paved the way towards individualized management. In addition, advancing knowledge of brain processing means that it is possible to take into consideration the interaction between the disease (low-grade glioma) and the host (the brain) and thus to modulate the therapeutic strategies with the goal to increase the median survival as well as to improve the quality of life.


Diffuse Low-Grade Gliomas in Adults: Natural History, Interaction with the Brain, and New Individualized Therapeutic Strategies presents the latest research pertaining to the diagnosis, therapy and management of diffuse low-grade gliomas (DLGG) in adults, with a particular focus on the path towards individualized therapy for this kind of tumor.  Recent research on the natural history of DLGGs and their interaction with the brain has led to new diagnostic and therapeutic strategies which increase survival and quality of life of the patient, and these methods are described in this book.


This book uniquely focuses on addressing diffuse low-grade gliomas in adults and is a valuable resource for medical oncologists, neuro-oncologists and neurologists.


DLGG Gliomagenesis

Editors and affiliations

  • Hugues Duffau
    • 1
  1. 1., INSERM U1051Institute for Neurosciences of MontpelliMontpellierFrance

Bibliographic information