Brain Ischemia

Basic Concepts and Clinical Relevance

  • Louis R. Caplan

Table of contents

  1. Front Matter
    Pages i-xiii
  2. The Brain

    1. Front Matter
      Pages 1-1
    2. Louis R. Caplan
      Pages 3-6
    3. J. H. Garcia
      Pages 7-18
    4. D. W. Choi
      Pages 29-36
    5. S. P. Finklestein
      Pages 37-41
    6. M. D. O’Brien
      Pages 43-50
    7. Louis R. Caplan
      Pages 51-56
  3. The Eye

    1. Front Matter
      Pages 57-57
    2. Louis R. Caplan
      Pages 59-60
    3. T. R. Hedges
      Pages 61-73
    4. Louis R. Caplan
      Pages 75-79
  4. The Blood

    1. Front Matter
      Pages 81-81
    2. Louis R. Caplan
      Pages 83-84
    3. W. M. Feinberg
      Pages 85-96
    4. M. J. Fisher
      Pages 97-103
    5. Louis R. Caplan
      Pages 121-126
  5. The Blood Vessels

    1. Front Matter
      Pages 127-127
    2. Louis R. Caplan
      Pages 129-133
    3. M. Fisher
      Pages 135-150
    4. J. D. Trachtenberg, U. S. Ryan
      Pages 173-183
    5. H. Schmid-Schönbein, K. Perktold
      Pages 185-213
    6. M. Hommel, F. Gray
      Pages 215-222
    7. Louis R. Caplan
      Pages 223-231
  6. Blood Flow, Blood Pressure and Intracranial Pressure

    1. Front Matter
      Pages 233-233
    2. Louis R. Caplan
      Pages 235-236
    3. J. C. Grotta
      Pages 261-267
    4. Louis R. Caplan
      Pages 289-294
  7. The Heart

    1. Front Matter
      Pages 295-295
    2. Louis R. Caplan
      Pages 297-298
    3. J. P. Hanna, A. J. Furlan
      Pages 299-315
    4. A. S. Ali, S. R. Levine
      Pages 317-328
    5. Louis R. Caplan
      Pages 329-334
  8. Clinical Research: Epidemiology Statistics, Databases and Trials

    1. Front Matter
      Pages 335-335
    2. Louis R. Caplan
      Pages 337-341
    3. P. B. Gorelick
      Pages 343-353
    4. D. B. Hier
      Pages 355-363
    5. Louis R. Caplan
      Pages 365-368
  9. Back Matter
    Pages 369-380

About this book


Professor Caplan has extensively edited the book to shape and organize the contents into a succinct presentation by experts of the basic science and clinical aspects of the topic. The text has been divided into sections: The Brain.- Macroscopic and microscopic molecular aspects of brain ischemia, including pathophysiology, pathology, biochemistry, and clinical measurement.- Blood Vessels.- Their constitution and the pathology and physiology of the endothelium and arterial wall.- Blood Flow.- Its physics, control, rheology, and pathophysiology.- Blood.- The role of the cellular and serological constituents in coagulation and fibrinolysis. - Heart.- Sources of embolism and cardiac changes caused by brain ischemia.- And Epidemiology, Databases, and Trials. Prefatory remarks by Professor Caplan introduce each section. At the end of each section he relates the basic concepts to patient problems in the clinic, integrates the various contributions in the section, and covers other areas not discussed by the individual contributors.


PET biochemistry brain cerebral ischemia intracranial pressure neuroprotection pathophysiology physiology positron emission tomography (PET) stroke tomography

Editors and affiliations

  • Louis R. Caplan
    • 1
  1. 1.Department of NeurologyNew England Medical Center HospitalsBostonUSA

Bibliographic information