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Cellular and Molecular Biology of Atherosclerosis

  • Antonio M. GottoJr

Part of the Argenteuil Symposia book series (ARGENTEUIL)

Table of contents

  1. Front Matter
    Pages i-xv
  2. J. A. Berliner, M. Territo, A. Amdalibi, M. Navab, F. Liao, S. Cushing et al.
    Pages 77-81
  3. L. Chan, W. Hide, Yau-Wen Yang, Wen-Hsiung Li
    Pages 93-107
  4. J. F. Oram
    Pages 145-152
  5. G. Assmann, A. von Eckardstein, H. Funke
    Pages 159-166
  6. Back Matter
    Pages 177-180

About this book

Introduction

Atherosclerotic cardiovascular disease remains the major cause of death and disability in Western society. The field of atherosclerosis research has grown tremendously over the last forty years, shedding a great deal of light on the contributing factors and natural history of the disorder and enabling strategies for its treatment and prevention. Some of the greatest strides in this field in recent years have derived from advances in molecular biology techniques. These strides were chosen for emphasis in the most recent Princess Lilian symposium, whose proceedings this volume represents. Historically, the Princess Lilian meetings have been small ones aimed at bringing together investigators from diverse specialties to discuss a particular subject. The most recent meeting was no exception and included clinicians, clinical investigators, and research­ ers in basic science. The symposium began with an extensive review of coronary morphopathological findings in patients who died of coronary heart disease. Any rational hypothesis of atherogenesis must take into account clinical findings, and any attempt to bridge the gap between experimental laboratory findings and studies in man is highly desirable. Three chapters focus on endothelial injury: one on the nitric oxide pathway in physiology and pathology, a second on the activation of endothelial cells, and a third on the monocyte and endothelial injury. Still another chapter examines growth factors, in particular the fibroblast growth factor in atherogenesis.

Keywords

Arterien Arterienverkalkung atherosclerosis biology cardiovascular cells endothelium heart lipoprotein metabolism molecular biology nitric oxide physiology protein vascular disease

Editors and affiliations

  • Antonio M. GottoJr
    • 1
  1. 1.The Methodist Hospital and Baylor College of MedicineHoustonUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4471-1909-8
  • Copyright Information Springer-Verlag London 1992
  • Publisher Name Springer, London
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4471-1911-1
  • Online ISBN 978-1-4471-1909-8
  • Series Print ISSN 1431-004X
  • Buy this book on publisher's site