Cardiac Remodeling and Failure

  • Pawan K. Singal
  • Ian M. C. Dixon
  • Lorrie A. Kirshenbaum
  • Naranjan S. Dhalla

Part of the Progress in Experimental Cardiology book series (PREC, volume 5)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Heart Failure and Therapies

    1. Front Matter
      Pages 1-1
    2. Bernhard Maisch, Arsen D. Ristić, Rainer Funck, Peter Alter, Susanne Kölsch, Annette Richter et al.
      Pages 35-65
    3. Ruth A. Altschuld, Bethany J. Holycross, M. Judith Radin, Sylvia A. McCune
      Pages 67-74
    4. Jos M. J. Lamers, Karin Eizema, Karel Bezstarosti, Henry Fechner, Sonja Schneider-Rasp, Haili Wang et al.
      Pages 87-101
    5. Hasso Scholz, Stephanie Läer, Frederike Behn, Michele Eiselt, Thomas S. Mir, Jochen Weil
      Pages 123-133
    6. Rajesh Dash, Evangelia G. Kranias
      Pages 135-152
    7. Emmanuel Camors, Ioulia Belikova, Virginie Monceau, Danièle Charlemagne
      Pages 153-163
    8. Peter VanBuren, Mark Hünlich, David Fishbaugher, Teuro Noguchi
      Pages 165-179
  3. Remodeling and Heart Failure

    1. Front Matter
      Pages 181-181
    2. Atushi Takeda, Yasuyuki Tanaka, Chihiro Shikata, Nobuakira Takeda
      Pages 195-203
    3. L. Henry Edmunds Jr, Joseph H. Gorman III, Robert C. Gorman
      Pages 231-243
    4. Keiko Yamauchi-Takihara, Hisao Hirota, Yasushi Fujio, Masahiro Izumi, Yuichi Oshima, Yoshikazu Nakaoka
      Pages 259-264

About this book

Introduction

According to the World Health Report (2000 http:/ /www. who. int/whr), of the 55 million deaths worldwide in 1999, more than 16 million were secondary to car­ diovascular complications. With the prospect of world population increasing from the current level of 6 billion to 9 billion by the middle of this century, the burden of cardiac disease is going to increase astronomically. Furthermore, scientists are being challenged not only to reduce mortality, but also to improve quality of life. Thus, more than ever, intellectuals from different disciplines including biology, sociology, informatics and health care have to join forces to meet the mandate. The World Heart Congress with a focus on "Frontiers in Cardiovascular Health" held in Winnipeg during July 6-11, 2001, made a unique attempt to bring these specialists together to brainstorm and map out the course of action for cardiovascular research and health in the next century. Anytime there is a relative increase in the workload on the heart, there are adap­ tive myocardial as well as humoral responses. When these adaptations or remodel­ ing at the organ, subcellular or gene level, become inadequate for a proper tissue perfusion, the condition of heart failure ensues. Prevention of the factors leading to the relative increase in workload as well as a better understanding of the adap­ tive responses and their failure are some of the hopes to combat the morbidity and mortality due to heart failure.

Keywords

Angiotensin II atherosclerosis atrial fibrillation cardiovascular cardiovascular function gene therapy heart hemodynamics vascular disease

Editors and affiliations

  • Pawan K. Singal
    • 1
  • Ian M. C. Dixon
    • 1
  • Lorrie A. Kirshenbaum
    • 1
  • Naranjan S. Dhalla
    • 1
  1. 1.Institute of Cardiovascular Sciences, St. Boniface General Hospital Research Centre, Faculty of MedicineUniversity of ManitobaWinnipegCanada

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4419-9262-8
  • Copyright Information Kluwer Academic Publishers 2003
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-4864-1
  • Online ISBN 978-1-4419-9262-8
  • Series Print ISSN 1389-1774
  • About this book