The Biology of Skeletal Metastases

  • Evan T. Keller
  • Leland W. K. Chung

Part of the Cancer Treatment and Research book series (CTAR, volume 118)

Table of contents

  1. Front Matter
    Pages i-xxi
  2. Victoria L. Robinson, Eric C. Kauffman, Mitchell H. Sokoloff, Carrie W. Rinker-Schaeffer
    Pages 1-21
  3. Shi-Ming Tu, Sue-Hwa Lin
    Pages 23-46
  4. Thomas J. Rosol, Sarah H. Tannehill-Gregg, Stephanie Corn, Abraham Schneider, Laurie K. McCauley
    Pages 47-81
  5. G. David Roodman, Sun Jin Choi
    Pages 83-100
  6. Jeffrey Kiefer, Angela Alexander, Mary C. Farach-Carson
    Pages 101-124
  7. Laurie K. McCauley, Abraham Schneider
    Pages 125-147
  8. Julie M. Brown, Jian Zhang, Evan T. Keller
    Pages 149-172
  9. R. Daniel Bonfil, Pamela Osenkowski, Rafael Fridman, Michael L. Cher
    Pages 173-195
  10. Theresa A. Guise, Khalid S. Mohammad
    Pages 197-212
  11. Toshiyuki Yoneda, Nobuyuki Hashimoto, Toru Hiraga
    Pages 213-229
  12. Chia-Ling Hsieh, Hiroyuki Kubo, Leland W. K. Chung
    Pages 231-290
  13. Carlton R. Cooper, Robert A. Sikes, Brian E. Nicholson, Yan-Xi Sun, Kenneth J. Pienta, Russell S. Taichman
    Pages 291-309
  14. Martine P. Roudier, Eva Corey, Lawrence D. True, Celestia S. Hiagno, Susan M. Ott, Robert L. Vessella
    Pages 311-339
  15. Back Matter
    Pages 341-344

About this book


Metastasis to bone is a common event in cancer. However, due to the skeleton's unique structure, exploring how cancer cells target the skeleton and interact with the bone microenvironment is challenging. The Biology of Skeletal Metastases covers areas that are important to both clinicians and basic scientists seeking an enhanced understanding of mechanisms of skeletal metastasis, as well as descriptions of cutting edge therapies for skeletal metastases.

Both increased efforts by many investigators and advances in research methodologies have provided a wealth of information in the area of skeletal metastases. The Biology of Skeletal Metastases brings together experts to describe these many advances. This book provides background in basic bone biology and biology of metastasis for novice investigators and highlights many advances in this challenging field for the experienced investigator.


biology bisphosphonates cancer cell environment gene therapy genes metastasis prostate cancer protein

Editors and affiliations

  • Evan T. Keller
    • 1
  • Leland W. K. Chung
    • 2
  1. 1.University of Michigan Comprehensive Cancer Center University of Michigan School of MedicineUniversity of MichiganAnn ArborUSA
  2. 2.Emory University School of MedicineEmory UniversityAtlantaUSA

Bibliographic information

  • DOI
  • Copyright Information Kluwer Academic Publishers 2004
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-4803-0
  • Online ISBN 978-1-4419-9129-4
  • Series Print ISSN 0927-3042
  • Buy this book on publisher's site