© 2003

High-Throughput Analysis

A Tool for Combinatorial Materials Science

  • Radislav A. Potyrailo
  • Eric J. Amis

Table of contents

  1. Front Matter
    Pages i-xxiii
  2. Elements of High-Throughput Analysis in Combinatorial Materials Science

    1. Radislav A. Potyrailo, Eric J. Amis
      Pages 1-13
  3. Economic Impact of Combinatorial Materials Science on Industry and Society [1]

  4. Optical Imaging and Spectroscopy

    1. Front Matter
      Pages 31-31
    2. Alamgir Karim, Amit Sehgal, J. Carson Meredith, Alfred J. Crosby, Eric J. Amis
      Pages 33-56
    3. Steven S. Lasko, Reed J. Hendershot, Yu Fu, Mark-Florian Fellmann, Gudbjorg Oskarsdottir, Christopher M. Snively et al.
      Pages 77-91
    4. Alan W. Schwabacher, Christopher W. Johnson, Peter Geissinger
      Pages 93-104
  5. Separations and Mass Spectrometry

    1. Front Matter
      Pages 105-105
    2. Miroslav Petro, Son Hoai Nguyen, Han-Ting Chang
      Pages 107-123
    3. Pierre-Alain W. Weiss, Jens w. Saalfrank, Jens Scheidtmann, Wilhelm F. Maier, Hans-Werner Schmidt
      Pages 125-153
    4. David Sýkora, Frantisek Svec, Jean M. J. Fréchet, Miroslav Petro, Adam L. Safir
      Pages 155-186
    5. Catherine A. Srebalus Barnes, David E. Clemmer
      Pages 187-216
  6. Sensors and Sensor Arrays

    1. Front Matter
      Pages 217-217
    2. Radislav A. Potyrailo, William G. Morris, Ronald J. Wroczynski
      Pages 219-246
    3. Yusuke Yamada, Tetsuhiko Kobayashi
      Pages 247-259
    4. Kerstin Kröger, Michael Seidel, Günter Gauglitz
      Pages 261-288
    5. Jaime C. Grunlan, Dennis Saunders, Jay Akhave, Mark Licon, Marcel Murga, Aaron Chavira et al.
      Pages 289-316
    6. Peter Geissinger, Alan W. Schwabacher
      Pages 317-345
  7. Analysis of Mechanical, Electrical, and Thermal Properties

    1. Front Matter
      Pages 347-347

About this book


This book, edited by Potyrailo and Amis, addresses a new paradigm-shifting approach in the search for new materials-Combinatorial Materials Science. One way to consider such an approach is to imagine an adventurous chef who decides to look for new entrees by cooking food ingredients in many pots using different combinations in every pot, and boil­ ing, steaming, or frying them in various ways. Although most of the pots will not have the tastiest food ever devised, some recipes will taste intriguing, and some eventually will lead to a discovery of a new fascinating cuisine. Of course, having a skilled chef design the com­ binatorial formulation will certainly be helpful in ensuring a successful outcome. Similar to food, each engineering material is a complex product of its chemical composition, structure, and processing. Generally, each of these components matters---change one and you get another material. Most of these "new" materials will be less good than ones we use now since existing materials have been refined with the extensive work of scientists and engi­ neers. At the same time if one prepares diverse materials like our adventurous chef, chang­ ing material composition, processing conditions and time, etc. , some of these materials will be superior to existing ones and a few might represent breakout technology.


alloy composite electrochemistry materials science polymer polymers spectroscopy

Editors and affiliations

  • Radislav A. Potyrailo
    • 1
  • Eric J. Amis
    • 2
  1. 1.GE Global ResearchSchenectady
  2. 2.National Institute of Standards and TechnologyGaithersburg

Bibliographic information


"This book should serve as a valuable resource for those graduate students, scientists, and engineers, who are interested in accelerating their research using combinatorial technologies."
(J.J. Hanak, Ph.D.)
"High-Throughput Analysis will serve as an invaluable resource for practitioners and new comers to the field. With the ingenuity and diligent efforts of scientists and engineers working in this field, I am convinced that combinatorial materials sciences will greatly enhance our understanding and ability to solve the problems of complex materials systems in the 21st century."
(X.D. Xiang, Ph.D.)
"With examples drawn from electronics, polymer chemistry, catalysis, biomaterials, metallurgy, and inorganic materials, this book reviews the state-of-the-art developments in analytical instrumentation that are critical to the success of combinatorial materials science. This book will be invaluable to industrial and academic scientists and engineers, as well as graduate students interested in the developments of sensors and other types of miniaturized analytical instrumentation for rapid characterization of materials on a combinatorial scale."
(Scott C. Donnelly, Senior VP, GE Global Research, Schenectady, NY)