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Antibodies

Volume 1: Production and Purification

  • G. Subramanian

Table of contents

  1. Front Matter
    Pages i-xiv
  2. David J. Glover, David P. Humphreys
    Pages 25-73
  3. Lothar R. Jacob, Matthias Frech
    Pages 101-131
  4. Caroline Vandevyver, Ruth Freitag
    Pages 133-168
  5. Andreas Richter, Mark Jostameling, Kerstin Müller, Andreas Herrmann, Martin Pitschke
    Pages 169-187
  6. Christophe de Romeuf, Christine Gaucher, Arnaud Glacet, Sylvie Jorieux, Philippe Klein, Dominique Bourel
    Pages 189-198
  7. John Bray, Malcolm K. Brattle
    Pages 199-225
  8. Leo A. van der Pol, Douwe F. Westra
    Pages 227-247
  9. David B. Haughey, Paula M. Jardieu
    Pages 249-273
  10. Back Matter
    Pages 289-314

About this book

Introduction

If the antibody industry is to achieve its full potential in the next decade, the individual technical potentials must be exploited, the limitations must be addressed, and lessons learned must be applied both to current purification methods and to the new technologies that continue to emerge. This book presents an overview of the current advances applied in the manufacture of monoclonal antibody including:
-concepts in development of manufacturing strategies,
-importance of antibody fragments,
-application of chromatography method development,
-quality control,
-effect of expression on antibody properties,
-virus removal and safety,
-pharmacokinetics,
-regulatory aspects.

Keywords

HIV cancer cancer therapy development future immunotherapy kinetics manufacturing pharmaceutical pharmacodynamics pharmacokinetics research safety tissue virus

Editors and affiliations

  • G. Subramanian
    • 1
  1. 1.LittlebourneUK

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4419-8875-1
  • Copyright Information Kluwer Academic/Plenum Publishers, New York 2004
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-4701-9
  • Online ISBN 978-1-4419-8875-1
  • Buy this book on publisher's site