Neurobiology of Actin

From Neurulation to Synaptic Function

  • Gianluca Gallo
  • Lorene M. Lanier

Part of the Advances in Neurobiology book series (NEUROBIOL, volume 5)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Kenneth A. Myers, Peter W. Baas
    Pages 73-96
  3. M. Elizabeth Ross, Stanislav Kholmanskikh
    Pages 139-160
  4. Annette Gärtner, Carlos G. Dotti
    Pages 161-176
  5. Barbara W. Bernstein, Michael T. Maloney, James R. Bamburg
    Pages 201-234
  6. Catherine Irene Dubreuil, David L. Van Vactor
    Pages 235-263
  7. Back Matter
    Pages 265-282

About this book

Introduction

Neurons are characterized by a complex, dynamic and highly polarized morphology. Actin and its regulatory proteins are the most abundant set of proteins within cells, and they form one of the major cytoskeletal systems—the actin filament cytoskeleton. While much has been learned about the roles of the actin cytoskeleton in non-neuronal cells, our understanding of the full spectrum of the functions of actin in neurons is far from complete. This book is an introduction to the interface between the actin cytoskeleton and the myriad of issues fundamental to the understanding of nervous system function. Neurobiology of Actin: From Neurulation to Synaptic Function opens with a chapter that presents the fundamental concepts required to appreciate the details of the molecular machinery that regulates actin in a cellular context, setting the stage for the first part of the book which reviews the neurobiology of actin at the cellular level. The second section of the book then discusses the functions of actin in the context of neurobiological issues ranging from early development to synaptic function and disease states of the nervous system. This text is intended for neuroscientists interested in investigating the actin cytoskeleton in the context of their particular neuroscience research program, and its chapters are cross-referenced in order to assist readers in finding relevant information that is covered in greater depth in other chapters.

Keywords

Actin Gallo Lanier Neurobiology

Editors and affiliations

  • Gianluca Gallo
    • 1
  • Lorene M. Lanier
    • 2
  1. 1., Dept Neurobiology and AnatomyDrexel University College of MedicinePhiladelphiaUSA
  2. 2.4-140 MCB, Department of NeuroscienceUniversity of MinnesotaMinneapolisUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4419-7368-9
  • Copyright Information Springer Science+Business Media, LLC 2011
  • Publisher Name Springer, New York, NY
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-4419-7367-2
  • Online ISBN 978-1-4419-7368-9
  • Series Print ISSN 2190-5215
  • Series Online ISSN 2190-5223
  • About this book