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The Cell Biology of Stem Cells

  • Eran Meshorer
  • Kathrin Plath

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 695)

Table of contents

  1. Front Matter
    Pages i-xx
  2. Yojiro Yamanaka, Amy Ralston
    Pages 1-13
  3. Kelly J. Morris, Mita Chotalia, Ana Pombo
    Pages 14-25
  4. Eleni M. Tomazou, Alexander Meissner
    Pages 26-40
  5. Peter J. Stambrook, Elisia D. Tichy
    Pages 59-75
  6. Jian-Chien Dominic Heng, Huck-Hui Ng
    Pages 76-91
  7. David A. Nelles, Gene W. Yeo
    Pages 92-104
  8. Tahsin Stefan Barakat, Joost Gribnau
    Pages 132-154
  9. Francesca Ferraro, Cristina Lo Celso, David Scadden
    Pages 155-168
  10. Ying Zhuge, Zhao-Jun Liu, Omaida C. Velazquez
    Pages 169-183
  11. Christopher L. Antos, Elly M. Tanaka
    Pages 184-214
  12. Masato Nakagawa, Shinya Yamanaka
    Pages 215-224
  13. Back Matter
    Pages 225-229

About this book

Introduction

Stem cells have been gaining a lot of attention in recent years. Their unique potential to self-renew and differentiate has turned them into an attractive model for the study of basic biological questions such as cell division, replication, transcription, cell fate decisions, and more. With embryonic stem (ES) cells that can generate each cell type in the mammalian body and adult stem cells that are able to give rise to the cells within a given lineage, basic questions at different developmental stages can be addressed. Importantly, both adult and embryonic stem cells provide an excellent tool for cell therapy, making stem cell research ever more pertinent to regenerative medicine. As the title The Cell Biology of Stem Cells suggests, our book deals with multiple aspects of stem cell biology, ranging from their basic molecular characteristics to the in vivo stem cell trafficking of adult stem cells and the adult stem-cell niche, and ends with a visit to regeneration and cell fate reprogramming. In the first chapter, “Early embryonic cell fate decisions in the mouse”, Amy Ralson and Yojiro Yamanaka describe the mechanisms that support early developmental decisions in the mouse pre-implantation embryo and the current understanding of the source of the most immature stem cell types, which includes ES cells, trophoblast stem (TS) cells and extraembryonic endoderm stem (XEN) cells.

Keywords

Activation Chromosome Telomere Vivo evolution genes miRNAs regulation

Editors and affiliations

  • Eran Meshorer
    • 1
  • Kathrin Plath
    • 2
  1. 1.Department of Genetics, Institute of Life SciencesThe Hebrew University of JerusalemJerusalemIsrael
  2. 2.Department of Biological ChemistryUCLA School of MedicineLos AngelesUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4419-7037-4
  • Copyright Information Landes Bioscience and Springer Science+Business Media, LLC 2010
  • Publisher Name Springer, Boston, MA
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-4419-7036-7
  • Online ISBN 978-1-4419-7037-4
  • Series Print ISSN 0065-2598
  • Buy this book on publisher's site