Advances in TNF Family Research

Proceedings of the 12th International TNF Conference, 2009

  • David Wallach
  • Andrew Kovalenko
  • Marc Feldmann

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 691)

Table of contents

  1. Front Matter
    Pages i-xxxvi
  2. Roles of the TNF Family in Tissue Homeostasis and Normal Development

    1. Front Matter
      Pages 1-1
    2. Andreas Leibbrandt, Josef M. Penninger
      Pages 5-22
    3. Kevin L. Bentley, Sharon Stranford, Shan Liao, Rawad M. Mounzer, Frank H. Ruddle, Nancy H. Ruddle
      Pages 35-44
    4. Tatsushi Igaki, Hiroshi Kanda, Hideyuki Okano, Tian Xu, Masayuki Miura
      Pages 45-50
  3. Novel Aspects of Signaling Activation by the TNF Family: Novel Aspects of the Functions of the TRAFs and cIAPs

  4. Novel Aspects of Signaling Activation by the TNF: Ubiquitin Modification of Signaling Proteins

    1. Front Matter
      Pages 93-93
    2. Fumiyo Ikeda, Simin Rahighi, Soichi Wakatsuki, Ivan Dikic
      Pages 107-114
    3. Christoph H. Emmerich, Anna C. Schmukle, Tobias L. Haas, Björn Gerlach, Stefanie M. Cordier, Eva Rieser et al.
      Pages 115-126
  5. Novel aspects of Signaling Activation by the TNF Family: TNF Signaling and Gene Regulatory Networks

About these proceedings


The biennial TNF-family conferences have been held over the past 20 years, from the time that TNF was cloned. These meetings have followed the enormous progress in this field. Much is now known about the members of the TNF ligand and receptor families, their signaling proteins, mechanisms of action and cellular functions. This volume is the proceedings of the 12th TNF International Conference, held in April 2009. This conference focuses on the physiological, pathophysiological, and medical significance of these important regulators. Sessions at the meeting specifically address their involvement in immunity, development, apoptosis, autoimmunity, cancer, and infection, the normal function and pathology of the neuronal system, as well as major unresolved questions about their mechanisms of action.

Editors and affiliations

  • David Wallach
    • 1
  • Andrew Kovalenko
    • 2
  • Marc Feldmann
    • 3
  1. 1.Dept. Biological ChemistryWeizmann Institute of ScienceRehovotIsrael
  2. 2.Dept. Biological ChemistryWeizmann Institute of ScienceRehovotIsrael
  3. 3.Kennedy Institute of RheumatologyImperial College LondonLondonUnited Kingdom

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2011
  • Publisher Name Springer, New York, NY
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-4419-6611-7
  • Online ISBN 978-1-4419-6612-4
  • Series Print ISSN 0065-2598
  • About this book