Cancer Genetics

  • Boris Pasche

Part of the Cancer Treatment and Research book series (CTAR, volume 155)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Kenneth Offit, Peter Thom
    Pages 1-14
  3. Diana Eccles, William Tapper
    Pages 15-32
  4. Kasmintan Schrader, David Huntsman
    Pages 33-63
  5. Mario Capasso, Sharon J. Diskin
    Pages 65-84
  6. Naresh Bellam, Boris Pasche
    Pages 85-103
  7. Back Matter
    Pages 105-112

About this book


Cancer genetics has revolutionized the practice of medicine as inherited genetic information helps predicts which individuals are at risk of developing various forms of cancer. Furthermore, somatically acquired genetic changes help identify therapeutic targets for patients with several common tumor types such as breast and colon cancer. Cancer Genetics reviews seminal discoveries such as genetic susceptibility to gastric cancer, ethical issues related to cancer genetics, the role of common variants in the development of breast cancer, novel genetic findings related to neuroblastoma, and the role of constitutively decreased TGF-beta signaling, which is emerging as one of the most common causes of colorectal cancer. The book has been written for all clinicians and researchers interested in cancer genetics, including oncologists, genetic counselors and cancer researchers both in academia and in industry. "Genetic alterations are a fundamental component of all cancers. This text highlights critical issues relevant for both basic scientists and clinicians. Recognized thought leaders in the field discuss current knowledge and future challenges." - Steven T. Rosen, M.D., Series Editor


Colorectal cancer GIST Methylation Ovarian Cancer Paragangliomas Prostate Cancer genetics

Editors and affiliations

  • Boris Pasche
    • 1
  1. 1.The UAB Comprehensive Cancer Center, Division of Hematology/OncologyThe University of Alabama at BirminghamBirminghamUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2010
  • Publisher Name Springer, Boston, MA
  • eBook Packages Medicine
  • Print ISBN 978-1-4419-6032-0
  • Online ISBN 978-1-4419-6033-7
  • Series Print ISSN 0927-3042
  • Buy this book on publisher's site