Antibiotic Policies

Controlling Hospital Acquired Infection

  • Ian M. Gould
  • Jos W.M. van der Meer

Table of contents

  1. Front Matter
    Pages 1-12
  2. Eimear Brannigan, Alison Holmes
    Pages 1-14
  3. Ian M. Gould
    Pages 15-25
  4. Yoshiro Hayashi, David L. Paterson
    Pages 27-38
  5. Ed J. Kuijper, S. Johnson, A. Goorhuis, M. H. Wilcox
    Pages 53-62
  6. Evelina Tacconelli, G. De Angelis
    Pages 63-79
  7. Peter M. Hawkey
    Pages 91-104
  8. Mitchell J. Schwaber, Yehuda Carmeli, Stephan Harbarth
    Pages 105-115
  9. Paschalis Vergidis, Matthew E. Falagas
    Pages 117-125
  10. Cara Winters, Hellen Gelband
    Pages 141-162
  11. Kevin Outterson, Olga Yevtukhova
    Pages 163-181
  12. Inge C. Gyssens, Jos W. M. van der Meer
    Pages 183-202
  13. Back Matter
    Pages 209-209

About this book


Hospitals worldwide are currently suffering an epidemic of infections, generated in and spreading in those instituitions whose very “raison d’etre” is to protect and improve the health of their patients. This paradox comes at a time of possibly unprecedented investment in preventative measures (infection control). To better control these infections, however, we need to understand their causes, many of which are related, paradoxically, to the success of antibiotic therapy. It is possible that the golden era of antibiotics led subconsciously to a loss of emphasis on the importance of hygiene in the control of HAI. Moreover, the majority of HAIs are due to multiply antibiotic resistant bacteria whose emergence has been hastened by over-enthusiastic antibiotic prescribing. Accumulating evidence also suggests that antibiotics not only select for resistance but can actually increase the numbers of HAIs and even their virulence.


This comprehensive compilation, written by eminent international researchers, explores these hypothesis in the context of recent epidemiology and evidence for the success of various antibiotic stewardship measures in controlling and even reversing resistance. It contains chapters by acclaimed authors on all the major causes of HAI, including MRSA, VRE, Clostridium difficile and multi resistant gram negative infections which are increasingly pan-resistant and untreatable; the nearest thing we have yet experienced to a “Doomsday bug”.


This book is an excellent source of information for students, researchers and practitioners in infection control, hospital epidemiology, antimicrobial prescribing and microbiology.

Editors and affiliations

  • Ian M. Gould
    • 1
  • Jos W.M. van der Meer
    • 2
  1. 1.Medical SchoolUniversity of AberdeenAberdeenUnited Kingdom
  2. 2.University Hospital NijmegenNijmegenNetherlands

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2012
  • Publisher Name Springer, New York, NY
  • eBook Packages Medicine
  • Print ISBN 978-1-4419-1733-1
  • Online ISBN 978-1-4419-1734-8
  • Buy this book on publisher's site