The Principles of Clinical Cytogenetics

  • Steven L. Gersen
  • Martha B. Keagle

Table of contents

  1. Front Matter
    Pages i-x
  2. Basic Concepts and Background

    1. Front Matter
      Pages 1-1
    2. Steven L. Gersen
      Pages 3-8
    3. Martha B. Keagle
      Pages 9-21
    4. Marilyn L. Slovak, Aaron Theisen, Lisa G. Shaffer
      Pages 23-49
  3. Examining and Analyzing Chromosomes

    1. Front Matter
      Pages 51-51
    2. Martha B. Keagle, Steven L. Gersen
      Pages 53-65
    3. Nathan S. Claxton, Stephen T. Ross
      Pages 67-76
    4. Martha B. Keagle
      Pages 77-94
    5. Steven L. Gersen
      Pages 95-109
  4. Clinical Cytogenetics

    1. Front Matter
      Pages 111-111
    2. Jin-Chen C. Wang
      Pages 113-137
    3. Kathleen Kaiser-Rogers, Kathleen W. Rao
      Pages 139-174
    4. Linda Marie Randolph
      Pages 213-227
    5. Linda Marie Randolph
      Pages 229-273
    6. Solveig M. V. Pflueger
      Pages 275-292
    7. Xiao-Xiang Zhang
      Pages 293-305
  5. Cancer Cytogenetics

    1. Front Matter
      Pages 307-307
    2. Aurelia Meloni-Ehrig
      Pages 309-370
    3. Linda D. Cooley, Kathleen S. Wilson
      Pages 371-411
  6. Adjunct Technologies

    1. Front Matter
      Pages 413-413
    2. Daynna J. Wolff
      Pages 415-439
    3. Lisa G. Shaffer
      Pages 441-450
  7. Beyond Chromosomes

    1. Front Matter
      Pages 451-451
    2. Jin-Chen C. Wang
      Pages 473-498
    3. Sarah Hutchings Clark
      Pages 499-513
  8. Back Matter
    Pages 515-569

About this book


In this thoroughly revised and expanded third edition of the highly praised classic, The Principles of Clinical Cytogenetics, a panel of hands-on experts update their descriptions of the basic concepts and interpretations involved in chromosome analysis to include the many advances that have occurred in the field. Among the highlights are a full chapter devoted to advances in chromosome microarray, soon to become a standard of care in this field, as well as an update on chromosome nomenclature as reflected in ISCN 2009. Other features include an update on automation to reflect the current state of the art, an update on hematopoietic neoplasms to reflect the new WHO guidelines, and updates on all regulatory changes that have been implemented.

Cutting edge and readily accessible, The Principles of Clinical Cytogenetics, Third Edition offers physicians who depend on the cytogenetics laboratory for the diagnosis of their patients, students in cytogenetics programs, graduate and medical students studying for board examinations, cytogenetics technologists, and cytogeneticists a clear understanding of what happens in the cytogenetics laboratory to facilitate accurate and timely diagnoses.


Cancer cytogenetics Chromosome microarray Fragile X Human chromosome nomenclature Prenatal cytogenetics

Editors and affiliations

  • Steven L. Gersen
    • 1
  • Martha B. Keagle
    • 2
  1. 1.AmeriPath NortheastSheltonUSA
  2. 2., Department of Allied HealthUniversity of ConnecticutStorrsUSA

Bibliographic information