New Aspects of Axonal Structure and Function

  • Dirk Feldmeyer
  • Joachim H.R. Lübke

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Axons in Development

    1. Front Matter
      Pages 1-1
    2. Esther T. Stoeckli, Vera Niederkofler
      Pages 3-18
    3. Zoltán Molnár, Wei Zhi Wang, Maria Carmen Piñon, Daniel Blakey, Shinichi Kondo, Franziska Oeschger et al.
      Pages 19-31
  3. Axonal Function

    1. Front Matter
      Pages 33-33
    2. Tony Kelly, Christine R. Rose
      Pages 35-53
    3. Dominique Debanne, Sami Boudkkazi
      Pages 55-83
    4. Gunnar Birke, Dietmar Schmitz, Andreas Draguhn
      Pages 85-102
    5. Quan Wen, Dmitri B. Chklovskii
      Pages 103-113
  4. Axons and Neuronal Circuits

    1. Front Matter
      Pages 115-115
    2. Tom Binzegger, Rodney J. Douglas, Kevan A.C. Martin
      Pages 117-139
  5. Axons and Degeneration/Regeneration

    1. Front Matter
      Pages 179-179
    2. Lucy J. Broom, V. Hugh Perry
      Pages 181-207
    3. Sven Hendrix, Robert Nitsch
      Pages 209-232
  6. Back Matter
    Pages 233-237

About this book


For any neuronal cell type, axons are unique neuronal output elements that display very heterogeneous patterns with respect to shape, length, and target structure. New Aspects of Axonal Structure and Function summarizes recent findings covering morphological, physiological, developmental, computational, and pathophysiological aspects of axons. The book covers new findings concerning axonal structure and functions together with their implications for signal transduction in the nervous system. The book also describes the processes implicated in the formation of axonal arbors and the transport of subcellular elements to their targets. Finally, New Aspects of Axonal Structure and Function also shows how a dysfunction in one or several of these steps could lead to axonal degeneration and ultimately to neurodegenerative diseases.

New Aspects of Axonal Structure and Function can be used as a reference for neuroscientists, neurophysiologists, neuroanatomists, computational neuroscientists, cellular neuroscientists, as well as Ph.D. students in various neuroscience programs.

About the Editors:
Dirk Feldmeyer was born in Dortmund, Germany and studied Biology and German literature and linguistics at the Ruhr-University in Bochum where he received his Ph.D. in 1987. In 2001, he obtained a postdoctoral fellowship in the Dept. of Pharmacology, University College London. He joined the Dept. of Cell Physiology, at the Max Planck Institute of Medical Research in 1995 and in 2004 became independent group leader at the Institute of Medicine, Research Centre Jülich. In 2008 he was appointed to a professorship on "Function of Cortical Microcircuits" in the Dept. of Psychiatry and Psychotherapy, RWTH Aachen University, Germany. His research interests are neuronal microcircuits in the neocortex, their development and modulation.

Joachim H.R. Lübke was born on November 4, 1956 in Gelsenkirchen and trained as a biological-technical assistant. He studied biology at the Georg-August University of Göttingen and did his Ph.D. at the Max Planck Institute for Biophysical Chemistry (Head: Prof. Otto-Detlev Creutzfeld). From 1991-1993 he was a postdoctoral fellow of the Royal Society at the Dept. of Human Anatomy (Head: Prof. Ray Guillery) of the University of Oxford. From there he moved as a "von Helmholtz" fellow of the German ministry of Eduction and Research to the Institute of Anatomy at the Albert-Ludwigs University Freiburg (Head: Prof. Michael Frotscher). In 1997 he received the Wolfgang-Bargmann prize of the German Anatomical Society. He did his "habilitation" in anatomy and neuroanatomy in 1999 and was appointed assistant professor at the Department of Anatomy of the University of Freiburg in 2000. In 2003 he was appointed to group leader position at the Institute of Medicine, Research Centre Jülich. He was appointed professor at the Faculty of Medicine of the Heinrich-Heine-University Düsseldorf. In 2008 he was also appointed to a Professorship on "Structure of Cortical Functional Units" at the Dept. of Psychiatry and Psychotherapy, RWTH Aachen University, Germany.


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Editors and affiliations

  • Dirk Feldmeyer
    • 1
  • Joachim H.R. Lübke
    • 2
  1. 1.Institute for Neurosciences MedicineForschungszentrum JülichJülichGermany
  2. 2.Institute of Neuroscience and MedicineForschungszentrum JülichJülichGermany

Bibliographic information