SuperMEN1

Pituitary, Parathyroid and Pancreas

  • Katalin Balogh
  • Attila Patocs

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 668)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Peter Igaz
    Pages 1-15
  3. Maria Papaconstantinou, Bart M. Maslikowski, Alicia N. Pepper, Pierre-André Bédard
    Pages 27-36
  4. Geoffrey N. Hendy, Hiroshi Kaji, Lucie Canaff
    Pages 37-50
  5. Ivan Maillard, Jay L. Hess
    Pages 51-57
  6. Hiroshi Kaji, Lucie Canaffand, Geoffrey N. Hendy
    Pages 59-67
  7. Colin Davenport, Amar Agha
    Pages 79-86
  8. Terry C. Lairmore, Herbert Chen
    Pages 87-95
  9. Attila Patocs, Katalin Balogh, Karoly Racz
    Pages 97-103
  10. Dheepa Balasubramanian, Peter C. Scacheri
    Pages 105-115
  11. Back Matter
    Pages 117-118

About this book

Introduction

The vast expansion in research on tumorigenesis has greatly increased our understanding of tumor development in patients with inherited endocrine tumor syndromes. This book provides an up-to-date summaryfrom clinical basics and latest follow-up guidelines to the most recent molecular findings in multiple endocrine neoplasia Type I syndrome. Articles have been assembled by acknowledged experts in their respective fields to provide current perspectives on the clinical and genetic backgroundsofthis syndrome and to review carefully the latest discoveries concerning the possible functions and interactions ofmenin, the protein encoded by the MEN1gene,including itspossible role incell cycle regulation,hematopoiesis,and bone development. The goal ofthe book is also to present the most recent findings and the broadest aspects of the role of menin in tumorigenesis of the endocrine glands involved in MEN I syndrome (pituitary, parathyroid, endocrine pancreas and adrenal). The connection between the basic experimental and clinical points of view are highlighted through a discussion on animal models, which explores the field in both an inspiring and questioning manner with a focus on areas that remain to be clarified. Our goal was to bring together clinicians and basic researchers who represent a wide range of interests in this particular field of endocrine oncology. Presentingacomprehensive and current overviewofbasic experimental and clinical findings, this book can bring us closer to understanding endocrine tumorigenesis in multiple endocrine neoplasia Type I. Katalin Balogh, MD, PhD Attita Patocs, MD, MSc, PhD v ABOUT THEEDITORS. . .

Keywords

Pancreas cell endocrine gland neuroendocrine tumor oncology protein tumor tumorigenesis

Editors and affiliations

  • Katalin Balogh
    • 1
  • Attila Patocs
    • 2
  1. 1.2nd Department of Medicine, Faculty of MedicineSemmelweis UniversityBudapestHungary
  2. 2.Hungarian Academy of Sciences Molecular Medicine Research Group and 2nd Department of Medicine, Faculty of MedicineSemmelweis UniversityBudapestHungary

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4419-1664-8
  • Copyright Information Springer-Verlag New York 2010
  • Publisher Name Springer, New York, NY
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-4419-1662-4
  • Online ISBN 978-1-4419-1664-8
  • Series Print ISSN 0065-2598
  • About this book