Metabolic Basis of Obesity

  • Rexford S. Ahima

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Jose Galgani, Eric Ravussin
    Pages 1-23
  3. Keith Tornheim, Neil B. Ruderman
    Pages 25-51
  4. Jaswinder K. Sethi, Antonio J. Vidal-Puig
    Pages 53-68
  5. Rexford S. Ahima, Marcus D. Goncalves
    Pages 69-88
  6. Emilie Caron, Rexford S. Ahima
    Pages 89-107
  7. Yan Wang, Efi Kokkotou
    Pages 109-125
  8. R. Arlen Price
    Pages 127-138
  9. Hyeong-Kyu Park, Rexford S. Ahima
    Pages 139-154
  10. Rachana Shah, Muredach P. Reilly
    Pages 155-173
  11. Sudha B. Biddinger, Brice Emanuelli
    Pages 175-198
  12. Tomoaki Morioka, Rohit N. Kulkarni
    Pages 199-217
  13. Eleonore Maury, Kathryn Moynihan Ramsey, Joseph Bass
    Pages 229-255
  14. Gary Sweeney, Sheldon E. Litwin, Evan Dale Abel
    Pages 257-292
  15. Sue-Anne Toh, Michael Levin, Daniel J. Rader
    Pages 293-309
  16. Evelyn Hsu, Gary Wu
    Pages 311-330
  17. Moshood O. Olatinwo, Djana Harp, Winston Thompson, Hyeong-Kyu Park, Roland Mathews
    Pages 331-341
  18. Rexford S. Ahima
    Pages 359-379
  19. Back Matter
    Pages 381-391

About this book


The obesity epidemic has generated immense interest in recent years due to the wide-ranging and significant adverse health and economic consequences that surround the problem. Much attention has been focused on behaviors that lead to obesity, in particular to over consumption of energy-dense food and to sedentary lifestyle. However, obesity is an extremely complex condition with poorly defined pathogenesis. Thanks to greatly enhanced research in the area, the discovery of pathways in the brain and peripheral organs that mediate energy homeostasis has provided a framework for understanding the biological basis of obesity. Metabolic Basis of Obesity adds an important new dimension to the growing literature on obesity by offering a comprehensive review of specifically how metabolic imbalance culminates in obesity. Developed by a team of expert authors, this important title discusses the principles of energy balance, genetics of body weight regulation, hormones and adipokines, and metabolic pathways in the brain, liver, muscle and fat, to name just several of the areas covered. The book also examines the connection between obesity and diabetes, cardiovascular disease and other complications. Current and future diagnostic and treatment strategies are also reviewed. Comprehensive and timely, Metabolic Basis of Obesity is an essential reference for understanding the burgeoning problem of obesity.


Adipokines Adipose tissue Cardiac dysfunction Circadian rhythms Energy metabolism Female reproductive health Gastrointestinal hormones Genetics Hormones Insulin Lipodystrophy Metabolism Neural control Obesity Pancreatic beta cells

Editors and affiliations

  • Rexford S. Ahima
    • 1
  1. 1.School of Medicine, Div. Endocrinology, Diabetes, &University of PennsylvaniaPhiladelphiaUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2011
  • Publisher Name Springer, New York, NY
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-1-4419-1606-8
  • Online ISBN 978-1-4419-1607-5
  • Buy this book on publisher's site