© 1995

Single-Channel Recording

  • Bert Sakmann
  • Erwin Neher

Table of contents

  1. Front Matter
    Pages i-xxvii
  2. Introduction to Patch Clamping

    1. Front Matter
      Pages 1-1
    2. Reinhold Penner
      Pages 3-30
    3. Alain Marty, Erwin Neher
      Pages 31-52
    4. Stefan H. Heinemann
      Pages 53-91
  3. Methods

    1. Front Matter
      Pages 93-93
    2. F. J. Sigworth
      Pages 95-127
    3. Klaus Benndorf
      Pages 129-145
    4. Erwin Neher
      Pages 147-153
    5. Kevin D. Gillis
      Pages 155-198
    6. Jens Eilers, Ralf Schneggenburger, Arthur Konnerth
      Pages 213-229
    7. Robert H. Chow, Ludolf Von Rüden
      Pages 245-275
    8. Donald W. Hilgemann
      Pages 307-327
    9. Don W. McBride Jr., Owen P. Hamill
      Pages 329-340
    10. Walter Stühmer, Anant B. Parekh
      Pages 341-356
    11. J. K. Heinrich Hörber, Johannes Mosbacher, Walter Häberle
      Pages 375-393

About this book


Edited by the 1991 winners of the Nobel Prize in Physiology or Medicine, this Second Edition includes new chapters covering such applications as capacitance measurements; single-cell PCR measurements; whole-cell recording from brain slices in combination with imaging techniques; atomic force microscopy of cells and membranes attached to glass pipettes; and patch clamping.


cells channel imaging imaging techniques microscopy neher neurons physiology recording sakmann single single-channel soft soft cover

Editors and affiliations

  • Bert Sakmann
    • 1
  • Erwin Neher
    • 2
  1. 1.Department of Cell PhysiologyMax-Planck-Institute for Medical ResearchHeidelbergGermany
  2. 2.Department of Membrane BiophysicsMax-Planck-Institute for Biophysical ChemistryGöttingenGermany

Bibliographic information


From reviews of the First Edition:

"A landmark in the field of membrane biophysics." (Science)

"A first-class laboratory indispensable reference." (Neuroscience)