Chemokine Receptors and NeuroAIDS

Beyond Co-Receptor Function and Links to Other Neuropathologies

  • Olimpia Meucci

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Section I

    1. Front Matter
      Pages 4-4
    2. Olimpia Meucci
      Pages 1-2
  3. Section I

    1. Front Matter
      Pages 4-4
    2. Maria F. Chen, Samantha Soldan, Dennis L. Kolson
      Pages 5-31
    3. Tracy Fischer-Smith, Jay Rappaport
      Pages 33-50
    4. Kevin Tan, Avindra Nath, Ahmet Hoke
      Pages 51-85
    5. Anupam Banerjee, Michael R. Nonnemacher, Brian Wigdahl
      Pages 87-118
  4. Section II

    1. Front Matter
      Pages 148-148
    2. David Vergote, Christopher M. Overall, Christopher Power
      Pages 149-172
    3. Stéphane Mélik Parsadaniantz, Ghazal Banisadr, Philippe Sarret, William Rostène
      Pages 173-189
    4. Shyam S. Rao, Mahil Rao, Nicole Warrington, Joshua B. Rubin
      Pages 253-270
    5. Davide Ragozzino, Clotilde Lauro, Cristina Limatola
      Pages 301-316
  5. Section III

    1. Front Matter
      Pages 318-318
    2. Christine Happel, Changcheng Song, Mathew J. Finley, Thomas J. Rogers
      Pages 319-335

About this book

Introduction

Chemokines and their receptors are being recognized as an integral component of the nervous system implicated in fundamental aspects of development and homeostasis, such as neurotransmission, proliferation, differentiation, and neuronal-glial communication. Thus, their involvement in HIV neuropathology goes far beyond the co-receptors role and entails complex interactions of the chemokine system with different cell types and other regulators of neuronal function. The major goal of this volume is to review these topics in order to highlight alterations of chemokine physiology that may contribute to neuroAIDS and other neuropathologies.

This book will be of interest to neuroscientists, neurologists, virologists, pharmacologists, and students in these fields. 

About the Editor:

Olimpia Meucci, MD, PhD is a Professor of Pharmacology and Physiology & Microbiology and Immunology at Drexel University College of Medicine in Philadelphia, PA. Since her seminal discovery about the regulation of neuronal signaling by chemokines, her research has primarily focused on the physio-pathological roles of this important class of neuroimmune modulators in the central nervous system and their involvement in neuroAIDS. These studies have significantly contributed to current understanding of the cellular and molecular mechanisms of HIV-related neuropathology including the interaction of the chemokine system with drug of abuse, namely opiates, which continues to be a major area of investigation in the Meucci lab.

Keywords

Alzheimer Chemokine HIV HIV infection Nervous System bacteria infection neurons neuroscience neurotoxicity opioid physiology

Editors and affiliations

  • Olimpia Meucci
    • 1
  1. 1.Dept. Pharmacology & Physiology, & Institute of Molecular MedicineDrexel University College of MedicinePhiladelphiaUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4419-0793-6
  • Copyright Information Springer-Verlag New York 2010
  • Publisher Name Springer, New York, NY
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-4419-0792-9
  • Online ISBN 978-1-4419-0793-6
  • About this book