The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes

Neuropsychological Endophenotypes and Biomarkers

  • Michael S. Ritsner

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Methodological and Technological Advances

    1. Cinnamon S. Bloss, Trygve E. Bakken, Alexander H. Joyner, Nicholas J. Schork
      Pages 87-102
    2. Thomas J. Raedler, Harald Mischak, Holger Jahn, Klaus Wiedemann
      Pages 103-111
    3. Stephen I. Deutsch, Barbara L. Schwartz, Richard B. Rosse, John Mastropaolo, Ayman H. Fanous, Abraham Weizman et al.
      Pages 113-122
  3. Neuropsychological, Neurocognitive and Neurophysiological Domains

    1. Annamari Tuulio-Henriksson, Jonna Perälä, Irving I. Gottesman, Jaana Suvisaari
      Pages 125-140
    2. Renata Schoeman, Dana J. H. Niehaus, Liezl Koen, Jukka M. Leppänen
      Pages 163-176
    3. William P. Horan, Tiffany A. Greenwood, David L. Braff, Raquel E. Gur, Michael F. Green
      Pages 177-193
    4. Yue Chen, Daniel Norton, Ryan McBain
      Pages 211-220
    5. Patricia E. G. Bestelmeyer
      Pages 221-226
    6. Carolina Lopez, Marion Roberts, Janet Treasure
      Pages 227-237
    7. Vijay A. Mittal, Elaine F. Walker
      Pages 239-258
  4. Back Matter
    Pages 259-273

About this book


Neuropsychiatric disorders such as schizophrenia, mood disorders, Alzheimer’s disease, epilepsy, alcoholism, substance abuse and others are some of the most debilitating illnesses worldwide characterizing by the complexity of the causes, and lacking the laboratory tests that may promote diagnostic and prognostic procedures. Recent advances in neuroscience, genomic, genetic, proteomic and metabolomic knowledge and technologies have opened the way to searching biomarkers and endophenotypes, which may offer powerful and exciting opportunity to understand the etiology and the underlying pathophysiological mechanisms of neuropsychiatric disorders. The challenge now is to translate these advances into meaningful diagnostic and therapeutic advances.

This book offers a broad synthesis of the current knowledge about diverse topics of the biomarker and endophenotype strategies in neuropsychiatry. The book is organized into four interconnected volumes: “Neuropsychological Endophenotypes and Biomarkers” (with overview of methodological issues of the biomarker and endophenotype approaches in neuropsychiatry and some technological advances), “Neuroanatomical and Neuroimaging Endophenotypes and Biomarkers”, “Metabolic and Peripheral Biomarkers” and “Molecular Genetic and Genomic Markers”. The contributors are internationally and nationally recognized researchers and experts from 16 countries.

This four-volume handbook is intended for a broad spectrum of readers including neuroscientists, psychiatrists, neurologists, endocrinologists, pharmacologists, clinical psychologists, general practitioners, geriatricians, health care providers in the field of neurology and mental health interested in trends that have crystallized in the last decade, and trends that can be expected to further evolve in the coming years. It is hoped that this book will also be a useful resource for the teaching of psychiatry, neurology, psychology and mental health.


Alzheimer Biomarkers Endophenotype Genes bipolar disorder emotion mood disorder neurology neuroscience phenotype proteomics psychiatric disorder psychiatry translation

Editors and affiliations

  • Michael S. Ritsner
    • 1
    • 2
  1. 1.Israel Institute of TechnologyHaifa
  2. 2.Sha'ar Menashe Mental Health CenterHaderaIsrael

Bibliographic information