Neuroactive Steroids in Brain Function, Behavior and Neuropsychiatric Disorders

Novel Strategies for Research and Treatment

  • Michael S. Ritsner
  • Abraham Weizman

Table of contents

  1. Front Matter
    Pages i-xx
  2. Neuroactive Steroids and Brain Functions

    1. Ming-De Wang, Mozibur Rahman, Jessica Strömberg, Per Lundgren, David Haage, Inga-Maj Johansson et al.
      Pages 3-42
    2. Roberto C. Melcangi, Luis Miguel Garcia-Segura
      Pages 43-59
    3. Alejandro F. De Nicola, Luciana Pietranera, Juan Beauquis, Françoise Homo-Delarche, Flavia E. Saravia
      Pages 61-87
    4. Victor V. Chaban
      Pages 89-102
    5. Torbjörn Bückström, Vita Birzniece, Guillén Fernández, Inga-Maj Johansson, Kristiina Kask, Charlotte Lindblad et al.
      Pages 103-121
    6. Sonsoles de Lacalle, Bryan Hyler, Thomas Borowski
      Pages 123-141
    7. Suguru Kawato, Yasushi Hojo, Hideo Mukai, Gen Murakami, Mari Ogiue-Ikeda, Hirotaka Ishii et al.
      Pages 143-169
    8. Tibor Hajszan, Zsofia Hoyk, Luis Miguel Garcia-Segura, Arpad Parducz
      Pages 171-185
    9. Yuri B. Saalmann, Mike B. Calford
      Pages 187-200
    10. Colin J. Saldanha, Barney A. Schlinger
      Pages 201-216
    11. Ioannis Charalampopoulos, Christos Tsatsanis, Andrew N. Margioris, Elias Castanas, Achille Gravanis
      Pages 217-225
    12. Alexander W. Krug, Christian G. Ziegler, Stefan R. Bornstein
      Pages 227-239
    13. Rael D. Strous
      Pages 241-248
  3. Neuroactive Steroids and Neuropsychiatric Disorders

    1. Michael S. Ritsner, Anatoly Gibel, Yael Ratner, Abraham Weizman
      Pages 251-297
    2. Flavia di Michele, Carlo Caltagirone, Gianfranco Spalletta
      Pages 325-335
    3. Victoria M. Payne, Jason D. Kilts, Jennifer C. Naylor, Jennifer L. Strauss, Patrick S. Calhoun, Roger D. Madison et al.
      Pages 369-383
    4. Torbjörn Bückström, Lotta Andréen, Marie Bixo, Inger Björn, Guillén Fernández, Inga-Maj Johansson et al.
      Pages 423-433
    5. Erin M. MacKenzie, Glen B. Baker, Jean-Michel Le Mellédo
      Pages 435-447
    6. Akiko Dohi, Glenn H. Dillon, Meharvan Singh
      Pages 483-491
    7. Daniel Stein, Rachel Maayan, Ron Loewenthal, Abraham Weizman
      Pages 493-507
    8. Brett C. Ginsburg, Lisa R. Gerak, Lance R. McMahon, John D. Roache
      Pages 509-538
    9. Pavel Golubchik, Abraham Weizman
      Pages 539-553
  4. Back Matter
    Pages 555-559

About this book


Over the past few decades the involvement of neurosteroids in brain function and mental health has attracted much interest, not only from a neuroscience perspective, but also from clinical and therapeutic aspects. In recent years, much of the research has focused on the multifunctional position of neurosteroids in the nervous system. The areas that have been explored, in particular, are the cellular and molecular mechanisms involved in the activity of neurosteroids in the brain, the role of neurosteroids in brain development, neurodegeneration and neuroplasticity, and their pharmacological properties. The large increase in the number of publications highlights this amplified interest in neurosteroids. Over the last 7 years at least 400 papers have been published describing the putative role of neurosteroids in the modulation of basic brain function and in the etiology and treatment of psychiatric and neurological disorders. Contributors to this book are amongst the most active basic researchers and c- nicians in the field and provide new perspectives not only clarifying some of the ongoing controversies, but also proposing diverse aspects and new insights. The book is organized in two major sections: “Neuroactive steroids and brain function’, and ‘Neuroactive steroids and neuropsychiatric disorders”. Though the selection of topics has been influenced by the current state of the art and the issues that require further elaboration, one should not assume that these are the only significant issues at this time.


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Editors and affiliations

  • Michael S. Ritsner
    • 1
  • Abraham Weizman
    • 2
  1. 1.Sha'ar Menashe Mental Health CenterIsrael
  2. 2.Geha Mental Health CenterIsrael

Bibliographic information

  • DOI
  • Copyright Information Springer Netherlands 2008
  • Publisher Name Springer, Dordrecht
  • eBook Packages Medicine
  • Print ISBN 978-1-4020-6853-9
  • Online ISBN 978-1-4020-6854-6
  • Buy this book on publisher's site