Skeletal Muscle Repair and Regeneration

  • Stefano Schiaffino
  • Terence Partridge

Part of the Advances in Muscle Research book series (ADMR, volume 3)

Table of contents

  1. Front Matter
    Pages I-XIII
  2. Frank E. Stockdale
    Pages 1-18
  3. Graziella Messina, Stefano Biressi, Giulio Cossu
    Pages 65-84
  4. Po Zhao, Eric Hoffman
    Pages 85-106
  5. Roddy S. O’Connor, Grace K. Pavlath
    Pages 145-162
  6. Bruce M. Carlson
    Pages 163-180
  7. George Karpati, Maria J. Molnar
    Pages 199-216
  8. Tero A.H. Järvinen, Minna Kääriäinen, Ville Äärimaa, Markku Järvinen, Hannu Kalimo
    Pages 217-242
  9. James G. Tidball
    Pages 243-268
  10. Clarke R. Slater, Stefano Schiaffino
    Pages 303-334
  11. Tommaso Nastasi, Nadia Rosenthal
    Pages 335-358
  12. Andrew S. Brack, Thomas A. Rando
    Pages 359-374
  13. Back Matter
    Pages 375-379

About this book

Introduction

Skeletal muscle is the most abundant tissue of our body. Apart from its essential role in locomotion, it is also the body’s main store of carbohydrate and protein as well as being one of the principal generators of heat. Its proper maintenance and function are, therefore, essential. A severe acute loss of muscle function is potentially lethal and the debilitating effects of chronic decline in mobility are commonplace experience, so repair and maintenance of the tissue must by both rapid and effective. Since the middle of the last century we have progressively built up a comprehensive descriptive model of the allied mechanisms that maintain our muscles at a size and strength appropriate to the functional demands upon them and that rapidly repair damaged muscles. This volume is an assemblage of the collective experience from the pick of major research groups investigating these aspects of muscle cell biology. The topics range from correlation of changes in pattern of gene expression with the histological sequence during a regenerative episode to the distinctive insult-specific patterns of structural and functional outcome at the other end of the spectrum. The middle ground – who is doing what in this complex process – constitutes the meat of this sandwich.

Keywords

Hydra Regulation cell biology gene expression myogenesis the origin tissue transcription

Authors and affiliations

  • Stefano Schiaffino
    • 1
  • Terence Partridge
    • 2
  1. 1.University of Padova and Venetian Institute of Molecular Medicine (VIMM)PadovaItaly
  2. 2.Center for Genetic MedicineWashingtonUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4020-6768-6
  • Copyright Information Springer Science+Business Media B.V. 2008
  • Publisher Name Springer, Dordrecht
  • eBook Packages Medicine
  • Print ISBN 978-1-4020-6767-9
  • Online ISBN 978-1-4020-6768-6
  • Series Print ISSN 1571-5663
  • About this book