Selected Aspects of Cancer Progression: Metastasis, Apoptosis and Immune Response

  • Hans E. Kaiser
  • Aejaz Nasir

Part of the Cancer Growth and Progression book series (CAGP, volume 11)

Table of contents

  1. Front Matter
    Pages i-vi
  2. David T. Denhardt, Ann F. Chambers, Danny R. Welch
    Pages 1-10
  3. Alison L. Allan, Ann F. Chambers
    Pages 33-58
  4. Rakesh K. Singh, James E. Talmadge
    Pages 59-90
  5. László Kopper, István Peták
    Pages 103-113
  6. Alexandra Eichten, Karin E. de Visser, Lisa M. Coussens
    Pages 115-137
  7. Jo Van Ginderachter, Yuanqing Liu, Nick Devoogdt, Wim Noël, Lea Brys, Gholamreza Hassanzadeh Gh. et al.
    Pages 139-156
  8. Dirk Nagorsen, Vladia Monsurro, Francesco M. Marincola
    Pages 157-167
  9. Gerhard R. F. Krueger, L. Maximilian Buja
    Pages 193-222
  10. Michael E. Brandt, Gerhard R. F. Krueger, Guanyu Wang
    Pages 223-246
  11. Back Matter
    Pages 247-249

About this book


The processes of tumor metastasis, apoptosis and anti-tumor immune response are among the most complex yet rapidly advancing fields in the area of cancer research. This monograph presents a comprehensive coverage of the recent advances in the various key concepts in these fundamental aspects of human cancer. It would be of particular interest to members of the cancer research community, especially those who are actively involved in the study of basic and translational aspects of human cancer. Specifically, this volume includes authentic subject reviews by leading experts on the following aspects:

  • Control of tumor cell motility
  • Role of tumor-cell adhesion and migration in organ-selective metastasis-formation
  • Tumor heterogeneity in relation to invasion and metastasis and its clinical implications
  • Tumor angiogenesis, angioprevention, anti-angiogenic therapies and response
  • Role of apoptosis in the development, progression and therapy of cancer
  • Role of macrophages in tumor development and metastasis
  • Pathways of macrophage-mediated tumor progression
  • Abnormal variation of immune response against cancer
  • Immunological aspects of Marek’s disease virus (MDV)-induced lymphoma progression
  • A biodynamical model of human T-cell proliferative disorders
  • Current methodologies for characterization of tumor directed immune response.


Activation Macrophages angiogenesis apoptosis cancer cancer research cell immune response lymphoma metastasis migration pathology prevention tumor tumor progression

Editors and affiliations

  • Hans E. Kaiser
    • 1
    • 2
  • Aejaz Nasir
    • 3
  1. 1.Department of Pathology, School of MedicineUniversity of MarylandBaltimoreUSA
  2. 2.Department of Clinical PathologyUniversity of ViennaAustria
  3. 3.Department of Interdisciplinary Oncology-PathologyMoffit Cancer Center & Research InstituteTampaUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Netherlands 2008
  • Publisher Name Springer, Dordrecht
  • eBook Packages Medicine
  • Print ISBN 978-1-4020-6728-0
  • Online ISBN 978-1-4020-6729-7
  • Buy this book on publisher's site