Myosins

A Superfamily of Molecular Motors

  • Lynne M. Coluccio

Part of the Proteins and Cell Regulation book series (PROR, volume 7)

Table of contents

  1. Front Matter
    Pages I-XII
  2. Kenneth C. Holmes
    Pages 35-54
  3. Mohammed El-Mezgueldi, Clive R. Bagshaw
    Pages 55-93
  4. Lynne M. Coluccio
    Pages 95-124
  5. Christine R. Cremo, David J. Hartshorne
    Pages 171-222
  6. Mary Anne Conti, Sachiyo Kawamoto, Robert S. Adelstein
    Pages 223-264
  7. ANDRÉA DOSÉ, Jennifer Lin-Jones, Beth Burnside
    Pages 265-287
  8. James R. Sellers, Lois S. Weisman
    Pages 289-323
  9. Folma Buss, John Kendrick-Jones
    Pages 325-352
  10. Aziz El-Amraoui, Amel Bahloul, Christine Petit
    Pages 353-373
  11. Keiichi Yamamoto
    Pages 375-390
  12. Martin BÄhler
    Pages 391-401
  13. Melinda M. Divito, Richard E. Cheney
    Pages 403-419
  14. Karine FrÉnal, Bernardo J. Foth, Dominique Soldati
    Pages 421-440
  15. Erich T. Boger, Gregory I. Frolenkov, Thomas B. Friedman, Inna A. Belyantseva
    Pages 441-467
  16. Back Matter
    Pages 469-475

About this book

Introduction

Few would have predicted 20 years ago that myosins constitute a superfamily with at least two-dozen classes and that these molecular motors are involved in a multitude of intracellular activities including cell division, cell movement, intracellular transport and signal transduction. Application of state-of-the-art cellular and molecular biological, structural biological, genetic, biochemical and biophysical techniques has provided and continues to provide critical information regarding the structure–function relationship; and the cellular roles of various myosins in organisms as diverse as protozoa, yeast, plants and higher animals. The association of myosins with diseases including neurological disorders, immu- deficiencies, cardiomyopathies, hearing and vision loss testify to the importance of understanding the biochemical properties and cellular roles of myosins. The 16 chapters in this volume summarize the tremendous progress made in studying members of the myosin superfamily in recent years and offer critical insight into what future research will yield. I would like to express my sincere gratitude to the authors of this volume. It was a pleasure to work with each of you and I thank you for the considerable efforts in making this international endeavor possible. I also thank John Trinick from the University of Leeds, UK, for the elegant montage of images of single molecules of myosins on the cover, which beautifully shows the structures of some of these amazing molecules. The able assistance of Marlies Vlot from Springer and Indumadhi Srinivasan from Integra Software Services for production of the book is greatly appreciated.

Keywords

biological functions cell division migration molecular mechanisms proteins

Authors and affiliations

  • Lynne M. Coluccio
    • 1
  1. 1.Boston Biomedical Research InstituteWatertownUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4020-6519-4
  • Copyright Information Springer 2008
  • Publisher Name Springer, Dordrecht
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-4020-6516-3
  • Online ISBN 978-1-4020-6519-4
  • About this book