Cell Adhesion and Cytoskeletal Molecules in Metastasis

  • Anne E. Cress
  • Raymond B. Nagle
Part of the Cancer Metastasis – Biology and Treatment book series (CMBT, volume 9)

Table of contents

  1. Front Matter
    Pages I-XII
  2. Elisabeth L. Bair, Raymond B. Nagle
    Pages 1-18
  3. Tracy L. Davis, Aaron J. Goldman, Anne E. Cress
    Pages 19-46
  4. Ronald L. Heimark, Nelson R. Alexander
    Pages 47-67
  5. Isaac Rabinovitz, Kaylene J. Simpson
    Pages 69-90
  6. Sanjay Chauhan, Ryan Childers, Jennifer Himes, Andrea Pierce, Sabrina Sykes, Kelvin W. Pond et al.
    Pages 91-102
  7. Monika Schmelz, Anil Prasad
    Pages 103-122
  8. Bernard W. Futscher, Frederick E. Domann
    Pages 123-140
  9. Lori A. Hazlehurst
    Pages 163-177
  10. Thomas C. Sroka, Anne E. Cress, Kit S. Lam
    Pages 179-192
  11. Back Matter
    Pages 193-198

About this book

Introduction

In this volume, the expression of specific adhesion molecules within human cancer tissues are highlighted. The expression signatures from published DNA microarray and immunohistochemistry studies are detailed. The concept that the alteration of specific adhesion molecules influence the cancer migration ability and cancer damage responses is detailed in this volume; both features are essential for the survival of an invading tumor cell. Defining the minimal adhesion receptors preserved on cancer cells during tumor progression will define the metastatic adhesion signature. Understanding the metastatic adhesion signature will reveal vulnerabilities that could be exploited for the prevention and/or eradication of the invading cancer cell.

Keywords

Migration Regulation adhesion structures cancer damage response epithelium extracellular matrix tissue

Editors and affiliations

  • Anne E. Cress
    • 1
  • Raymond B. Nagle
    • 2
  1. 1.University of ArizonaTucsonU.S.A.
  2. 2.University of ArizonaTucsonU.S.A.

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4020-5129-6
  • Copyright Information Springer 2006
  • Publisher Name Springer, Dordrecht
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-4020-5128-9
  • Online ISBN 978-1-4020-5129-6
  • Series Print ISSN 1568-2102
  • About this book