Table of contents
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Preliminaries to Testing of Drugs in Man
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Organisation and Decision Making
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Ethical and Legal Considerations
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Measuring Drug Activity in Man
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Assessment of Drug Effects on the Cardiovascular System
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Assessment of Drug Effects on the Respiratory System
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Assessment of Drug Effects on the Central Nervous System
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Assessment of Drug Effects on the Gastrointestinal System
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Assessment of Drug Effects on the Kidney
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Assessment of the Effects of Drugs Used in Obstetrics and Gynaecology
About this book
Introduction
This book is a practical detailed and comprehensive guide for those involved in the conduct of early human studies with new drugs. It covers the pre-clinical information relevant to first human studies including pharmaceutical, metabolic, toxicological and regulatory aspects, as well as the general considerations relevant to all early human studies. Each major therapeutic area is considered by class of activity of drug. The chapters describe what measurements of drug activity are available in healthy human subjects and in patients, how to make the measurements, their value and their limitations. The contributors are drawn internationally both from the pharmaceutical industry and academia. The book provides a unique practical guide to all concerned with the development of new drugs.
Keywords
cardiovascular system drug kidney pharmaceutical pharmaceutical industry research
Editors and affiliations
Bibliographic information
- DOI https://doi.org/10.1007/978-1-349-10705-6
- Copyright Information Macmillan Publishers Limited 1990
- Publisher Name Palgrave, London
- eBook Packages Engineering
- Print ISBN 978-1-349-10707-0
- Online ISBN 978-1-349-10705-6
- Buy this book on publisher's site